Defensive potential and deleterious impact of turmeric (Curcuma longa) L rhizome powder supplemented diet on antioxidant status of indomethacin-induced ulcerated wistar rats.

Effects of various concentration of turmeric (Curcuma longa [C longa]) rhizome powder (TRP) supplemented diet on the antioxidant status of selected organs (stomach, liver, kidney, and heart) of indomethacin (Indo)-induced ulcerated wistar rats were investigated in this study. The rats were fed with different percentages of TRP supplemented diet (1% [A], 2% [B], 5% [C], and 10% [D]) for 28 days. It was observed from the results that animals fed on 10% turmeric rhizome supplemented and those in the ulcerogenic group had significant reduction in kidney, cardiac gluthione (GSH), superoxide dismutase (SOD), catalase (CAT), and gastric GSH when compared with normal control animals and other pre-treated groups.