Is Involved in Resistance to 7-Aminocholesterol and Secretion of Fungal Proteins in .

() is a pathogenic yeast that is the leading cause of fungal meningitis in immunocompromised patients. Various virulence factors, such as the enzyme laccase and its product melanin, phospholipase, and capsular polysaccharide have been identified. During a screen of knockout mutants, the gene resistance to aminocholesterol 1 () was identified, the function of which is currently unknown in .