Clovibactin and Staphylococcus aureus: a new weapon against resistant strains.

Clovibactin is a new depsipeptide and highly efficacious against () , including methicillin-resistant and vancomycin-resistant , with no apparent resistance. Clovibactin outclasses current antibiotics such as vancomycin. Here, we discuss its efficacy, emphasize the need for new antibiotics owing to growing global antibiotic resistance, highlight its mode of action and possible benefits over current treatments.

Meta-meta-analysis of the mortality risk associated with MRSA compared to MSSA bacteraemia.

bacteraemia (SAB) is a bloodstream infection that carries a high risk of exacerbating a diseased state and may result in an increased death rate. The aim of this study was to assess mortality risk in Methicillin Resistant (MRSA) bacteraemia compared to Methicillin Susceptible (MSSA) bacteraemia through meta-meta-analyses. The study followed PRISMA guidelines, conducting a comprehensive search in Scopus, PubMed, and Google Scholar.

A meta-meta-analysis of co-infection, secondary infections, and antimicrobial resistance in COVID-19 patients.

The newly discovered coronavirus SARS-CoV-2 has sparked a worldwide pandemic of COVID-19, which has caused havoc on medical infrastructures, economies, and cultures around the world. Determining the whole scenario is essential since SARS-CoV-2 variants and sub-variants keep appearing after vaccinations and booster doses. The objective of this secondary meta-analysis is to analysis co-infection, secondary infections, and antimicrobial resistance (AMR) in COVID-19 patients.

Prevalence, risk-factors, and antimicrobial susceptibility profile of methicillin-resistant Staphylococcus aureus (MRSA) obtained from nares of patients and staff of Sokoto state-owned hospitals in Nigeria.

The aim of the study was to determine the prevalence of methicillin-resistant (MRSA) obtained from the nasal cavity of participants and investigate the antibiotic resistance profiles of the isolates from Sokoto state, Nigeria. Nasal swabs of both nares were obtained from 378 participants across three study centers within the six-month study period. The isolates recovered were characterized, and their resistance phenotype determined in conjunction with MRSA prevalence.