Publications by authors named "Adeena Musheer"

Background: The role of corticosteroids in the treatment of community-acquired pneumonia (CAP) remains uncertain. We conducted an updated meta-analysis to investigate the effectiveness and potential effect modifiers of adjunctive corticosteroids in patients with CAP.

Methods: The protocol of this meta-analysis was registered with PROSPERO (CRD42022354920).

View Article and Find Full Text PDF

Introduction: The role of antibiotics in the development of inflammatory bowel disease (IBD) remains controversial, primarily due to conflicting data from individual studies. We conduct a systematic review and meta-analysis to study the effect of antibiotic exposure on IBD development.

Methodology: The MEDLINE and Cochrane CENTRAL databases were queried from their inception to April 2021 for published articles studying the association between antibiotic exposure and new-onset IBD.

View Article and Find Full Text PDF
Article Synopsis
  • Doctors looked at studies to see if new blood thinners called DOACs are safe and work well for cancer patients who have blood clots.
  • They found that DOACs reduce the chances of blood clots coming back compared to other treatments, like LMWH and VKAs.
  • While DOACs may have a bit of a bleeding risk, they are considered safer and better for most patients who have cancer-related blood clots.
View Article and Find Full Text PDF
Article Synopsis
  • Individualized guided selection of antiplatelet therapy, which uses genetic and platelet function testing, has the potential to improve outcomes for patients undergoing percutaneous coronary intervention (PCI) compared to standard therapy.
  • A systematic review pooled data from 11 clinical trials involving 18,465 patients and found that guided therapy significantly reduced major adverse cardiovascular events (MACE), heart attacks (MI), stent thrombosis (ST), strokes, and minor bleeding.
  • The results suggest that implementing genetic and platelet function testing can lead to better antiplatelet therapy choices for patients, ultimately enhancing their overall health outcomes.
View Article and Find Full Text PDF

Background: Many publications have compared various outcomes defining safety and efficacy of DOACs across different BMI ranges. Our meta-analysis compares warfarin and DOACs for its treatment effects over different BMI ranges.

Methods: A systematic search was conducted from inception to May 2021 on PubMed, Scopus and Embase databases.

View Article and Find Full Text PDF

Background: Various anticoagulant therapies are prescribed to patients under physicians' discretion and recently Direct Oral Anticoagulants(DOAC) have been under trials to evaluate their safety and efficacy. In addition to this, the regimen of DOACs and Aspirin is of keen interest as researchers continue to find an optimal regimen to treat blood clots in patients. This study is a systematic review and -analysis of randomized controlled trials and observational studies that asses the safety and efficacy of DOAC with and without Aspirin.

View Article and Find Full Text PDF

COVID-19 has proved to be a serious, and consequential disease that has affected millions of people globally. Previously, the adverse effects of proton pump inhibitors (PPI) have been observed with increasing the risk of pneumonia and COVID-19. This meta-analysis aims to address the relationship between the use of PPI and the severity of COVID-19 infection.

View Article and Find Full Text PDF
Article Synopsis
  • Dietetics plays a crucial role in research, revealing the cardiovascular benefits of healthy diets, notably through the consumption of organic foods and chili peppers (CP).
  • A search of major databases identified relevant studies on CP consumption, ultimately narrowing it down to four observational studies involving over 570,000 participants.
  • The analysis demonstrated that CP consumers had a significantly lower risk of all-cause mortality as well as reduced risks for cardiovascular diseases and cancer-related deaths, suggesting a strong association between CP consumption and improved health outcomes.
View Article and Find Full Text PDF