Publications by authors named "Adebolajo A Adeyemo"

Article Synopsis
  • The study developed a prediction model for aminoglycoside-induced ototoxicity (hearing loss) in a cohort of 153 adults undergoing anti-TB treatment with Streptomycin.
  • Key factors influencing the risk of ototoxicity included age, cumulative dosage of Streptomycin, and baseline hearing levels, with age and dosage significantly increasing the risk.
  • The model demonstrated good predictive ability, with training and validation areas under the curve indicating strong discrimination for identifying those at risk for hearing loss.
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Background: Aminoglycosides, such as Streptomycin, are cheap, potent antibiotics widely used Sub-Saharan Africa. However, aminoglycosides are the commonest cause of ototoxicity. The limited prospective epidemiological studies on aminoglycoside ototoxicity from Sub-Saharan Africa motivated this study to provide epidemiological information on Streptomycin-induced ototoxicity, identify risk factors and predictors of ototoxicity.

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Introduction: nasopharyngeal carcinoma is relatively common in our environment. It is one of the most difficult malignancies to diagnose at an early stage. The aim of the study was to determine the clinical features, clinical disease stage of nasopharyngeal carcinoma at presentation and at diagnosis as well as the histologic types at the University College Hospital, Ibadan, Nigeria.

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Disabling hearing loss as a sequela of bacterial meningitis results from damage to the auditory system. This study was designed to ascertain the hearing thresholds in survivors of bacterial meningitis and the risk factors of hearing loss in childhood bacterial meningitis. One hundred and two children admitted and treated for bacterial meningitis were recruited prospectively along with 102 age- and sex-matched controls who had auditory evaluation using otoacoustic emission and auditory brain stem response tests 48 h prior to hospital discharge.

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Background: Newborn hearing screening programs identifies newborns with hearing loss. The early identification enables prompt intervention through hearing rehabilitation. Accurate knowledge of the program and its benefit will impact on the uptake of the program by the citizenry.

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The goal of this study was to translate the LittlEARS Auditory Questionnaire into Yoruba language for use with Yoruba-speaking parents and to evaluate the psychometric properties of the Yoruba version of questionnaire. Translation of the LittlEARS Auditory Questionnaire into Yoruba language was done using a back-translation method. The study participants included 423 parents of normal hearing children aged 6-24 months.

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Quality of Life encompasses an individual's well-being and health, social participation and satisfaction with functional daily living. Disabilities such as deafness can impact on the quality of life with spatial variance to the environment. Deafness causes communicative problems with significant consequences in cognitive, social, and emotional well-being of affected individuals.

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Article Synopsis
  • Hearing impairment can result from various causes, including the ototoxic effects of aminoglycosides like streptomycin, especially in patients with certain mitochondrial gene mutations.
  • Many developing countries overuse aminoglycosides, worsening hearing impairment, but there's insufficient data to drive policy changes regarding their use.
  • This study aims to assess the incidence of ototoxicity in tuberculosis patients treated with streptomycin, analyze genetic factors, and provide insights that could lead to better treatment adherence and public health strategies.
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Background: Traumatic Brain Injury (TBI) is a significant cause of morbidity and mortality worldwide. Our previous studies showed a high frequency of motor vehicle accidents among neurosurgical patients. However, there is a dearth of data on head injuries in children in Nigeria.

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The nasogastric tube has been used frequently for enteral feeding and as an intranasal oxygen catheter. This practice is however associated with complications. We present a case of rhinosinusitis and sepsis in a diabetic patient following the insertion of a nasogastric tube.

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