Prevalence of lung function impairment in cured pulmonary tuberculosis patients in Cotonou, Benin.

Setting: National teaching hospital for the management of respiratory diseases, Cotonou, Benin.

Objective: 1) To estimate the prevalence of lung function impairment (LFI) and associated factors in patients cured of pulmonary tuberculosis (PTB); and 2) to determine the link between human immunodeficiency virus (HIV) infection and LFI occurrence.

Design: We performed a cross-sectional study in cured patients with smear-positive TB (PTB+) treated between 2012 and 2015.

Operational research within the national tuberculosis control programme in Benin.

Objective: To document whether the placement of operational research (OR) fellows within disease control programmes in low and middle income countries leads to the implementation of operational research and improvements in policy and practice.

Result: In 2012, an OR fellow was placed within the National TB Programme, Benin, to strengthen the implementation of operational research. From 2012 to 2015, eight OR projects were implemented, of which three contributed to changes in programme practice and five provided information which was not previously available from quarterly/annual reports.

Tuberculosis Case Finding in Benin, 2000-2014 and Beyond: A Retrospective Cohort and Time Series Study.

Objective. To determine any changes in tuberculosis epidemiology in the last 15 years in Benin, seasonal variations, and forecasted numbers of tuberculosis cases in the next five years. Materials and Methods.

Characteristics and Treatment Outcomes of Retreatment Tuberculosis Patients in Benin.

Objective. To determine among retreatment tuberculosis patients in Benin baseline characteristics, culture, and drug sensitivity testing (DST) results and treatment outcomes. Materials and Methods.

Follow-up and tracing of tuberculosis patients who fail to attend their scheduled appointments in Cotonou, Benin: a retrospective cohort study.

Background: In the "Centre National Hospitalier de Pneumo-Phtisiologie" of Cotonou, Benin, little is known about the characteristics of patients who have not attended their scheduled appointment, the results of tracing and the possible benefits on improving treatment outcomes. This study aimed to determine the contribution of tracing activities for those who missed scheduled appointments towards a successful treatment outcome.

Methods: A retrospective cohort study was carried out among all smear-positive pulmonary tuberculosis patients treated between January and September 2013.

Low prevalence of diabetes mellitus in patients with tuberculosis in Cotonou, Benin.

Setting: The three Basic Management Units (BMUs) of the National Tuberculosis Programme (NTP) in Cotonou, Benin.

Objective: To determine the prevalence of diabetes mellitus (DM) among tuberculosis (TB) patients in Cotonou.

Design: A cross-sectional study of consecutively registered TB patients treated for a minimum of 2 weeks between June and July 2014 in the three BMUs, with measurement of their fasting blood glucose (FBG).

[Sensitisation profile to airborne allergens of patients followed for asthma in Cotonou, Benin. A cross-sectional study using prick-tests].

Rationale: The sensitisation profile to airborne allergens of asthma patients followed in Benin is not known.

Patients And Methods: A descriptive cross-sectional study was conducted from April to June 2013 at the hospital reference centre. A prick-test was performed in all adults with asthma consulting during this period.

National profile and treatment outcomes of patients with extrapulmonary tuberculosis in Bénin.

Background: In sub-Saharan Africa, there is a dearth of published literature on extrapulmonary tuberculosis (EPTB).

Objective: To describe demographic, diagnostic and HIV-status characteristics of patients with EPTB in Bénin, their treatment outcomes, and among those who completed their treatment in the Centre National Hospitalier de Pneumo-Phtisiologie (CNHP-P), the proportion whose bodyweight increased during treatment.

Material And Findings: This was a retrospective cohort study with comparisons made between EPTB and new smear-positive pulmonary tuberculosis (NPTB) patients diagnosed in the country from January to December 2011.

[Evaluation of tuberculous patients' management when re-treated in Cotonou, Benin].

Retreatment of tuberculosis is the leading risk factor for drug resistance if the management is not adequate and complete. The objective of this study was to evaluate the management of cases of retreatment in Cotonou. This was a retrospective, descriptive cross type which covered a period of 5 years.

National profile and treatment outcomes of adult smear-negative pulmonary TB patients in Benin.

Background: In Benin, patients with smear-negative pulmonary TB (SNPTB) are of low priority in the National Tuberculosis Programme (NTP) and little is known about their profile or treatment outcomes.

Methods: A retrospective cohort study was carried out to determine characteristics and treatment outcomes in all adults registered with SNPTB in 2009. Findings were compared with patients with new smear-positive pulmonary tuberculosis (PTB) diagnosed in the same period.

MDR-TB treatment needs in patients previously treated for TB in Cotonou, Benin.

Setting: Centre National Hospitalier de Pneumo-Phtisi-ologie, Cotonou, Benin.

Objective: To determine the proportion of individuals needing treatment for multidrug-resistant tuberculosis (MDR-TB) among patients previously treated for TB.

Design: A retrospective cross-sectional study of all patients previously treated for TB in Cotonou from 2003 to 2011.

Management of asthma in Benin: the challenge of loss to follow-up.

Setting: An asthma pilot project in Benin.

Objective: To assess the implementation of standard case management of asthma at three referral centres and three primary care centres.

Methods: The project began with local adaptation of international asthma guidelines, followed by situation analysis, pre-intervention, training and intervention.

The burden and outcomes of childhood tuberculosis in Cotonou, Benin.

Setting: The National Tuberculosis Programme (NTP) and the paediatric ward of the General Hospital (GH), Cotonou, Benin.

Objective: To describe the burden of tuberculosis (TB), characteristics and outcomes among children treated in Cotonou from 2009 to 2011.

Design: Cross-sectional cohort study consisting of a retrospective record review of all children with TB aged <15 years.

Management of tuberculosis and HIV co-infection in Cotonou, Benin.

Objectives: The authors had for aim to assess the management of tuberculosis and HIV co-infection in Cotonou, Benin.

Patients And Methods: We made a cross-sectional, retrospective, and descriptive study comparing the clinical presentation and outcome of patients with tuberculosis and HIV co-infection versus patients with tuberculosis alone, all managed at the National Pneumophtisiology Center in Cotonou, Benin, in 2009.

Results: The rate of HIV screening in TB patients was 99%.

[Bronchoconstriction induced by exercise in the black African athlete].

Introduction: The bronchoconstriction induced by exercise (BIE) in urban black Africans is poorly known. The warm moist air would be a mitigating factor for its occurrence. The objective of this study was to measure the prevalence and determine the associated factors.

[Prevalence of respiratory disorders in women exposed to the smoke from smoking fish in the municipality of Cotonou, Benin].

Introduction: Women are constantly exposed to fumes and gases produced by burning wood, however they are poorly studied. The aim of this study was to assess the prevalence of respiratory disorders among women most at risk.

Subjects And Methods: We conducted a descriptive, transversal and prospective women engaged with the site of artisanal smoked fish Hwlacodji in Cotonou.

Exposure to combustion of solid fuel and tuberculosis: a matched case-control study.

The present study was conducted in Benin to ascertain the association between exposure to combustion of solid fuel (coal and biomass) and tuberculosis. Cases were consecutive, sputum smear-positive tuberculosis patients never previously treated for tuberculosis for as long as 1 month. Two controls were selected from the neighbourhood of each case, matched by age and sex by a predefined procedure.

[Mitochondrial toxicity: a case of palpebral ptosis in a woman infected by HIV and treated with HAART including zidovudine].

The usual clinical feature of mitochondrial toxicity is proximal myopathy. We present the report case of palpebral ptosis which occurred under zidovudine therapy The symptom remission was obtained by stopping the antiretroviral therapy. This involves an important vigilance from both doctor and patient.

Incidence of lipodystrophy and metabolic disorders in patients starting non-nucleoside reverse transcriptase inhibitors in Benin.

Background: The incidence and risk factors for lipodystrophy and metabolic disorders among patients in Africa on first-line combined antiretroviral treatment (cART) mostly containing non-nucleoside reverse transcriptase inhibitors is poorly documented.

Methods: This prospective cohort study recruited 88 HIV-infected patients initiating cART between October 2004 and June 2005 in Cotonou, Benin. Patients were followed for 24 months.

[Undesirable effect of antiretroviral drugs in patients infected with HIV at Cotonou Benin].

Objectives: Evaluate the tolerance of highly active antiretroviral therapy (HAART) on PLWHA treated in Cotonou to improve the quality of their follow up.

Methods: Retrospective study among PLWHA aged > or = 15 years, treated by HAART during the period February 2002 - January 2004 and who respond to one or more consultation of follow up. Adverse effects (AE) revealed by patients or noticed by the physician are analyzed.

[Epidemiological aspects of snakebites in Benin].

Among rural environmental health emergencies, snakebite was common in villages community and agriculture activities. Their frequency and fatal complication depend on the venomous character of the species and the lack of early treatment. The aim of this work was to describe some epidemiological aspects of the snakebites and to suggest preventive strategies to avoid complication.

[Morbidity of diabetic foot in Internal Medicine CNHU HKM, Cotonou].

The diabetes and its complications appear increasingly frequent in our medical practice. We fixed ourselves for objectives to determine the frequency of the foot diabetic in Internal Medicine at Cotonou, to count the factors etiopathogenic responsible for the lesions and to describe the clinical aspects of the lesions. We carried out a retrospective study on the 420 diabetics hospitalized of January 1, 1995 to December 31, 1999.

[Clinical and immunological profile of HIV infected patients in Cotonou, Benin].

Objectives: This study had for aim to identify the clinical status and the level of immuno-deficiency of HIV-infected patients on their first visit.

Methods: One hundred and thirty-six HIV+ patients were prospectively evaluated from November 1, 2001 to May 31, 2002.

Results: One hundred and thirty-four were infected with HIV1 and two with HIV2.

Suppression of nonradiative recombination by V-shaped pits in GaInN/GaN quantum wells produces a large increase in the light emission efficiency.

Despite the high density of threading dislocations generally found in (AlGaIn)N heterostructures, the light emission efficiency of such structures is exceptionally high. It has become common to attribute the high efficiency to compositional fluctuations or even phase separation in the active GaInN quantum well region. The resulting localization of charge carriers is thought to keep them from recombining nonradiatively at the defects.

Child malaria treatment practices among mothers in the district of Yanfolila, Sikasso region, Mali.

We studied child malaria treatment practices among mothers living in the District of Yanfolila in southern Mali. For sampling, we first chose five of 13 health areas with probability proportional to size. Then villages, compounds and mothers with at least one child aged 1-5 years were randomly chosen.