Single-cell assays have enriched our understanding of hematopoiesis and, more generally, stem and progenitor cell biology. However, these single-end-point approaches provide only a static snapshot of the state of a cell. To observe and measure dynamic changes that may instruct cell fate, we developed an approach for examining hematopoietic progenitor fate specification using long-term (> 7-day) single-cell time-lapse imaging for up to 13 generations with in situ fluorescence staining of primary human hematopoietic progenitors followed by algorithm-assisted lineage tracing.
View Article and Find Full Text PDFChild Adolesc Social Work J
March 2022
Although sub-Saharan Africa has the world's highest rates of early pregnancy, there is little awareness of pregnancy and parenting among young people in out-of-home care in this region. Therefore, this study looked into the experiences of pregnancy and parenting among young women who had been in residential care in Ghana and Uganda. We gathered data from ten parenting care leavers in both countries using semi-structured interviews and then analyzed the data from the interviews thematically.
View Article and Find Full Text PDFJ Microbiol Biol Educ
December 2021
We developed the "Who's in Class?" form with the major goals of increasing instructors': (1) awareness of their learners' diverse attributes and identities, and (2) implementation of inclusive teaching practices. This article provides an overview of the tool in addition to feedback from instructors who used the form, and their students' perspectives. Instructors taught a variety of courses at the undergraduate and master's levels.
View Article and Find Full Text PDFProblem: Clinical reasoning is a necessary skill for medical students to acquire in the course of their education, and there is evidence that they can start this process at the undergraduate level. However, physician educators who are experts in their given fields may have difficulty conveying their complex thought processes to students. Providing faculty development that equips educators with tools to teach clinical reasoning may support skill development in early medical students.
View Article and Find Full Text PDFEur Phys J C Part Fields
January 2015
The jet energy scale (JES) and its systematic uncertainty are determined for jets measured with the ATLAS detector using proton-proton collision data with a centre-of-mass energy of [Formula: see text] TeV corresponding to an integrated luminosity of [Formula: see text][Formula: see text]. Jets are reconstructed from energy deposits forming topological clusters of calorimeter cells using the anti-[Formula: see text] algorithm with distance parameters [Formula: see text] or [Formula: see text], and are calibrated using MC simulations. A residual JES correction is applied to account for differences between data and MC simulations.
View Article and Find Full Text PDFThis Letter presents a search for quantum black-hole production using 20.3 fb-1 of data collected with the ATLAS detector in pp collisions at the LHC at √s = 8 TeV. The quantum black holes are assumed to decay into a final state characterized by a lepton (electron or muon) and a jet.
View Article and Find Full Text PDFA search is presented for dark matter pair production in association with a W or Z boson in pp collisions representing 20.3 fb(-1) of integrated luminosity at √s=8 TeV using data recorded with the ATLAS detector at the Large Hadron Collider. Events with a hadronic jet with the jet mass consistent with a W or Z boson, and with large missing transverse momentum are analyzed.
View Article and Find Full Text PDFThis Letter presents measurements of the polarization of the top quark in top-antitop quark pair events, using 4.7 fb(-1) of proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider at √s=7 TeV. Final states containing one or two isolated leptons (electrons or muons) and jets are considered.
View Article and Find Full Text PDFEur Phys J C Part Fields
September 2014
This paper presents a study of the performance of the muon reconstruction in the analysis of proton-proton collisions at [Formula: see text] TeV at the LHC, recorded by the ATLAS detector in 2010. This performance is described in terms of reconstruction and isolation efficiencies and momentum resolutions for different classes of reconstructed muons. The results are obtained from an analysis of [Formula: see text] meson and [Formula: see text] boson decays to dimuons, reconstructed from a data sample corresponding to an integrated luminosity of 40 pb[Formula: see text].
View Article and Find Full Text PDFEur Phys J C Part Fields
July 2014
Many of the interesting physics processes to be measured at the LHC have a signature involving one or more isolated electrons. The electron reconstruction and identification efficiencies of the ATLAS detector at the LHC have been evaluated using proton-proton collision data collected in 2011 at [Formula: see text] TeV and corresponding to an integrated luminosity of 4.7 fb[Formula: see text].
View Article and Find Full Text PDFA measurement is presented of the [Formula: see text] production cross section at [Formula: see text] = 7 TeV using [Formula: see text] collision data corresponding to an integrated luminosity of 383 [Formula: see text], collected with the ATLAS experiment at the LHC. Selection of [Formula: see text](1020) mesons is based on the identification of charged kaons by their energy loss in the pixel detector. The differential cross section is measured as a function of the transverse momentum, [Formula: see text], and rapidity, [Formula: see text], of the [Formula: see text](1020) meson in the fiducial region 500 [Formula: see text] 1200 MeV, [Formula: see text] 0.
View Article and Find Full Text PDFMeasurements of the variation of inclusive jet suppression as a function of relative azimuthal angle, Δφ, with respect to the elliptic event plane provide insight into the path-length dependence of jet quenching. ATLAS has measured the Δφ dependence of jet yields in 0.14 nb(-1) of √(s(NN))=2.
View Article and Find Full Text PDFTwo-particle correlations in relative azimuthal angle (Δø) and pseudorapidity (Δη) are measured in sqrt[s(NN)] = 5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb(-1) of data as a function of transverse momentum (p(T)) and the transverse energy (ΣE(T)(Pb)) summed over 3.
View Article and Find Full Text PDFThe ATLAS experiment has observed 1995 Z boson candidates in data corresponding to 0.15 nb(-1) of integrated luminosity obtained in the 2011 LHC Pb+Pb run at sqrt[s(NN)]=2.76 TeV.
View Article and Find Full Text PDFResults of a search for new phenomena in events with an energetic photon and large missing transverse momentum in proton-proton collisions at sqrt[s] = 7 TeV are reported. Data collected by the ATLAS experiment at the LHC corresponding to an integrated luminosity of 4.6 fb(-1) are used.
View Article and Find Full Text PDFThis Letter presents a search for magnetic monopoles with the ATLAS detector at the CERN Large Hadron Collider using an integrated luminosity of 2.0 fb(-1) of pp collisions recorded at a center-of-mass energy of sqrt[s]=7 TeV. No event is found in the signal region, leading to an upper limit on the production cross section at 95% confidence level of 1.
View Article and Find Full Text PDFEur Phys J C Part Fields
August 2013
The luminosity calibration for the ATLAS detector at the LHC during collisions at [Formula: see text] in 2010 and 2011 is presented. Evaluation of the luminosity scale is performed using several luminosity-sensitive detectors, and comparisons are made of the long-term stability and accuracy of this calibration applied to the collisions at [Formula: see text]. A luminosity uncertainty of [Formula: see text] is obtained for the 47 pb of data delivered to ATLAS in 2010, and an uncertainty of [Formula: see text] is obtained for the 5.
View Article and Find Full Text PDFA search for a charged Higgs boson () in [Formula: see text] decays is presented, where one of the top quarks decays via →, followed by → two jets ([Formula: see text]). The other top quark decays to , where the boson then decays into a lepton (/) and a neutrino. The data were recorded in collisions at [Formula: see text] by the ATLAS detector at the LHC in 2011, and correspond to an integrated luminosity of 4.
View Article and Find Full Text PDFEur Phys J C Part Fields
May 2013
A measurement of splitting scales, as defined by the clustering algorithm, is presented for final states containing a boson produced in proton-proton collisions at a centre-of-mass energy of 7 TeV. The measurement is based on the full 2010 data sample corresponding to an integrated luminosity of 36 pb which was collected using the ATLAS detector at the CERN Large Hadron Collider. Cluster splitting scales are measured in events containing bosons decaying to electrons or muons.
View Article and Find Full Text PDFEur Phys J C Part Fields
March 2013
A search for supersymmetric particles in final states with zero, one, and two leptons, with and without jets identified as originating from -quarks, in 4.7 fb of [Formula: see text] collisions produced by the Large Hadron Collider and recorded by the ATLAS detector is presented. The search uses a set of variables carrying information on the event kinematics transverse and parallel to the beam line that are sensitive to several topologies expected in supersymmetry.
View Article and Find Full Text PDFEur Phys J C Part Fields
March 2013
A measurement of the top quark pair production cross section in the final state with a hadronically decaying tau lepton and jets is presented. The analysis is based on proton-proton collision data recorded by the ATLAS experiment at the LHC, with a centre-of-mass energy of 7 TeV. The data sample corresponds to an integrated luminosity of 1.
View Article and Find Full Text PDFEur Phys J C Part Fields
March 2013
The measurement of the jet energy resolution is presented using data recorded with the ATLAS detector in proton-proton collisions at [Formula: see text]. The sample corresponds to an integrated luminosity of 35 pb. Jets are reconstructed from energy deposits measured by the calorimeters and calibrated using different jet calibration schemes.
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