Publications by authors named "Adarshan S"
Article Synopsis
- Macroalgae, or seaweed, has gained global attention as a promising source for nutraceuticals and pharmaceuticals due to its genetic diversity and nutritional value, including proteins, vitamins, and bioactive compounds.
- These organisms play a crucial role in marine ecosystems and produce about 80% of the Earth's oxygen, emphasizing their ecological importance.
- The review highlights the significance of omics approaches in understanding macroalgae, advocating for further research to utilize their potential in developing new drugs, functional foods, and advancing sustainable industries.
The COVID-19 pandemic has been a global health crisis for over three years now, with the virus causing widespread illness and death. The urgent need for safe and effective therapeutic drugs has prompted the exploration of alternative medicine systems such as Ayurveda and Siddha. This study focuses on the potential therapeutic properties of the Ayurvedic plant, Mimusops elengi.
View Article and Find Full Text PDFis reported as a potent Indian medicinal plant that possesses numerous pharmacological activities due to the presence of various bioactive compounds. These pharmacological activities were used in the ancient medicine system to cure inflammatory conditions. Bacopa has the ability to reduce acute pain and inflammation by inhibiting the enzyme cyclo-oxygenase-2 () and reducing -arbitrated prostanoid mediators.
View Article and Find Full Text PDFCoronavirus disease (COVID-19) is a viral disease caused by the SARS-CoV-2 virus and is becoming a global threat again because of the higher transmission rate and lack of proper therapeutics as well as the rapid mutations in the genetic pattern of SARS-CoV-2. Despite vaccinations, the prevalence and recurrence of this infection are still on the rise, which urges the identification of potential global therapeutics for a complete cure. Plant-based alternative medicine is becoming popular worldwide because of its higher efficiency and minimal side effects.
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- Chronic obstructive pulmonary disease (COPD) is a severe and inflammatory condition that causes airway obstruction, leading to a high mortality rate and the need for advanced treatments like lung transplants or long-term oxygen therapy.
- The study explores the use of L., a medicinal plant known for its diverse metabolites, by employing systems pharmacology and molecular docking to identify its potential in treating COPD through multi-target mechanisms.
- Results revealed 86 specialized metabolites from L. that interact with over 1,300 human receptors, suggesting promising bioactive compounds; however, further clinical trials are necessary to confirm their efficacy against COPD.
In nature or field conditions, plants are frequently exposed to diverse environmental stressors. Among abiotic stresses, the low temperature of freezing conditions is a critical factor that influences plants, including horticultural crops, decreasing their growth, development, and eventually quality and productivity. Fortunately, plants have developed a mechanism to improve the tolerance to freezing during exposure to a range of low temperatures.
View Article and Find Full Text PDFCancer is one of the most common malignant diseases that occur worldwide, among which breast cancer is the second leading cause of death in women. The subtypes are associated with differences in the outcome and were selected for treatments according to the estrogen receptor, progesterone receptor, and human epidermal growth factor receptor. Triple-negative breast cancer, one of the subtypes of breast cancer, is difficult to treat and can even lead to death.
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