Publications by authors named "Adarsh P Varghese"
Article Synopsis
- Congenital heart disease (CHD) is linked to both clotting and bleeding risks, with past studies showing mixed results on platelet activity in affected infants, prompting this investigation.
- The study enrolled 19 infants with CHD and 21 controls, using advanced mass spectrometry to analyze platelet surface markers and cytokine levels in the blood.
- Results indicated significant differences in platelet activation in CHD infants, revealing unique subpopulations of platelets, increased hypogranular platelets, and elevated plasma cytokines, suggesting complex platelet behavior in this condition.