Phenotypic profile and antibiogram of biofilm-producing bacteria isolates from diabetic foot ulcers in Zaria, Nigeria.

Background: Diabetic foot ulcers (DFUs) present with high morbidity and reduce patient's quality of life. There is a gross paucity of data on biofilm-producing bacteria in DFU Infection in North-Western Nigeria. The study sought to determine the biofilm-forming ability of bacteria isolates from DFUs and determine their antimicrobial susceptibility pattern in Zaria, North-Western Nigeria.

Clinical and biochemical correlates of hypogonadism in men with type 2 diabetes mellitus.

Introduction: there is an association between hypogonadism and obesity, chronic hyperglycaemia, and ageing in men with type 2 diabetes mellitus (T2DM). T2DM is known to be associated with low testosterone. There is a paucity of data on the risk factors of hypogonadism in Nigerian men with T2DM.

Distribution of hepatitis B virus-positive individuals in Zaria, Nigeria, according to risk-associated practices.

Background: An estimated 75% of Nigerians are at risk of hepatitis B virus (HBV) exposure. In an attempt to reduce the menace, the assessment of risk factors associated with HBV infection and general perception of infected individuals is a step in that direction.

Aim Of The Study: This study, therefore, identified exposure to risk factors and general perceptions associated with HBV infection in infected individuals in Zaria, Nigeria.

The prevalence and clinical profile of adrenocortical deficiency among HIV infected persons in Northern Nigeria.

Background: Infection with the human immune deficiency virus (HIV) is still a prevalent problem in Africa.

Objectives: The aim of this study was to determine the prevalence of hypocortisolism among patients with HIV and their clinical profile at Aminu Kano Teaching Hospital (AKTH), Kano, Nigeria.

Method: Three hundred and fifty adult patients with HIV infection were recruited from the HIV clinic of AKTH, Kano.

Occurrence of hypocortisolism in HIV patients: Is the picture changing?

Background: The occurrence of endocrine diseases in people who are infected with HIV is traditionally thought to occur in the setting of AIDS with opportunistic infections and malignancies. However, recent studies find the correlation between hypocortisolism and stage of HIV (CD4 count and WHO clinical stage) inconsistent.

Methods: This descriptive cross-sectional study included three hundred and fifty (350) consecutive patients with HIV infection.

Low education and lack of spousal relationship are associated with dementia in older adults with diabetes mellitus in Nigeria.

Background: The relationship between dementia and type 2 diabetes mellitus (T2DM) in older adults is well established in the literature. However, there have been few studies on this relationship in older adults living in low- and middle-income countries, and most demographic projections predict that older adult population will increase substantially in these regions by 2050.

Methods: In this study, older adults with T2DM attending a tertiary health facility were examined and compared with community-dwelling older adults without T2DM.

Magnetic Resonance Imaging Determination of Normal Pituitary Gland Dimensions in Zaria, Northwest Nigerian Population.

Objectives: To determine the dimensions of normal pituitary gland using T1-weighted magnetic resonance images (MRI) and to determine their relationship with age and sex.

Materials And Methods: Cranial MRI scans of 100 individuals with clinically normal pituitary function (58 males and 42 females) and in the age range 14-82 years were reviewed in order to obtain volumetric measurements of the pituitary gland. The height, width, and depth of the pituitary were obtained from mid-sagittal and coronal planes, while the volume was calculated from these measured parameters.

Anti-retroviral therapy induced diabetes in a Nigerian.

Background: Anti-retroviral therapy (ART) using Highly Active Anti-retroviral Therapy (HAART) has led to considerable reduction in morbidity and mortality associated with human Immune deficiency virus (HIV) infection. This has led to increased life expectancy in HIV infected individuals on one hand, and side effects of chronic administration of these drugs on the other. One of such untoward effects is the association of anti-retroviral drugs especially the protease inhibitors (PI's) with metabolic derangements such as dyslipidaemia, lipodystrophy, insulin resistance and rarely Diabetes mellitus.

Genital tuberculosis presenting as pyrexia of undetermined origin.

A case of Genital tuberculosis in a female patient is presented. The key presenting features in this lady were chronic weight loss, colicky lower abdominal pains, fever, and amenorrhea. The fact that tuberculosis is still very much around and could present in unpredictable ways is emphasised.