Publications by authors named "Adamu Almustapha Aliero"

Trypanosomes are the causative agents of animal African trypanosomiasis (AAT) and human African trypanosomiasis (HAT), the former affecting domestic animals prevalent in Sub-Saharan Africa. The main species causing AAT in cattle are , , and . Northern Uganda has been politically unstable with no form of vector control in place.

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The current upsurge in resistance to conventional antibiotics, as well as high cost of orthodox medical treatment, called for the use of medicinal plants as an alternative therapy. This research was aimed at determining the antibacterial activity of seed extracts (Jackfruit as it is locally called) in the treatment of diarrhoea. Ethanolic and hexanolic seed crude extracts of the plant were screened for antidiarrhoeal activity against bacteria isolated from clinical samples (methicillin-resistant and susceptible multidrug-resistant , ciprofloxacin-resistant , and third-generation cephalosporin-resistant ).

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Bacterial infections are on a rise with causal-resistant strains increasing the economic burden to both patients and healthcare providers. Salons are recently reported as one of the sources for transmission of such resistant bacterial strains. The current study aimed at the identification of the prevalent bacteria and characterization of quaternary ammonium compound () genes from disinfectant-resistant isolated from salon tools in Ishaka town, Bushenyi District of Uganda.

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Introduction: bacterial resistance to fluoroquinolones is on the rise globally, bacteria causing urinary tract infections (UTIs) are no exception to this fact. Judicious use of the current antibiotics by clinicians is therefore deemed necessary to combat development of resistance. This study determined fluoroquinolone resistant profiles, multiple antibiotic resistance indices (MARI), factors associated with fluoroquinolone resistance and their strength among patients attending hospitals in Bushenyi District, Uganda.

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Article Synopsis
  • Dermatophyte infections, commonly overlooked in Uganda, were studied for prevalence and antifungal activity of ethanolic crude leaf extract in a sample of 100 patients at Kampala International University Teaching Hospital (KIU-TH).* -
  • Microscopy confirmed 49% of samples positive for dermatophytosis, with the highest rates found in individuals aged 11-30 years, while culture tests verified 57% of those cases, identifying a variety of both dermatophyte and non-dermatophyte fungi.* -
  • The ethanolic leaf extract demonstrated antifungal activity against dermatophytes, with minimum inhibitory concentrations ranging from 62.5 to 250 mg/ml, indicating potential for further development as a treatment.*
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Introduction: Superbugs are pathogenic micro-organism and especially a bacterium that has developed resistance to the medications normally used against it. As the superbug family increases, the need for appropriate diagnostic, treatment, prevention and control strategies cannot be over emphasized. Therefore, this work determined the distribution of superbug bacteria among patients on prolonged hospital admissions in three tertiary hospitals of Kano state, Nigeria.

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Urinary tract infections (UTIs) are one of the major causes of morbidity and comorbidities in patients with underlying conditions, and it accounts for the majority of the reasons for hospital visit globally. Sound knowledge of factors associated with UTI may allow timely intervention that can easily bring the disease under control. This study was designed to determine the prevalence of UTI by isolating and characterizing the different bacterial etiological agents and to evaluate the factors associated with UTI.

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