Correlation between LGR5 stem cells and location of tumor as well as age, sex and metastasis in colon adenocarcinoma.

Purpose: G-protein receptors belong to a large family of receptors which includes more than 800 kinds. An interest for these receptors arose upon noticing their expression on skin, intestine and breast stem cells.

Methods: We examined the tissues of 53 patients who had been diagnosed with adenocarcinoma of the colon.