Publications by authors named "Adamantia Mpratsiakou"
Background: High aldosterone levels contribute to kidney disease progression, while spironolactone in combination with ACEi or ARBs can potentially reduce proteinuria and ameliorate kidney function deterioration. However, evidence on the impact of eplerenone in patients with glomerulonephritis is scarce.
Methods: In this prospective observational study, we assessed the effects of eplerenone in patients with biopsy-proven glomerulonephritis who were already treated with ACEi or ARBs.
Article Synopsis
- Patients on maintenance hemodialysis exhibit a lower immune response to mRNA vaccines, influenced mainly by issues like older age and the uremic environment, but the impact of body composition parameters hasn't been fully explored.
- A study of 49 hemodialysis patients who received the BNT162b2 vaccine found that while most developed detectable antibody levels after vaccination, only 43% maintained protective titers three weeks post-second dose, declining to 24% after three months.
- The research indicated that longer durations on dialysis led to poorer antibody responses, with specific body composition metrics—like phase angle and prediction marker values—affecting the development and maintenance of protective antibody levels.
Introduction: Normal saline (N/S) and Ringer's-Lactate (L/R), are administered in everyday clinical practice. Despite that, N/S increases the risk of sodium overload and hyperchloremic metabolic acidosis. In contrast, L/R has lower sodium content, significantly less chloride and contains lactates.
View Article and Find Full Text PDFObjectives: The appearance of new onset diabetes is common after kidney transplant. Treatment options are limited because of renal function-related contraindications, interactions with immunosuppressive drugs, and side effects. We investigated the long-term safety and efficacy of dipeptidyl peptidase IV inhibitors in renal transplant recipients with new onset diabetes.
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