Publications by authors named "Adam Zienkiewicz"

Unlabelled: Background Antimicrobial-resistant (AMR) gonorrhoea is a global public health threat. Discriminatory point-of-care tests (POCT) to detect drug sensitivity are under development, enabling individualised resistance-guided therapy.

Methods: An individual-based dynamic transmission model of gonorrhoea infection in MSM living in London has been developed, incorporating ciprofloxacin-sensitive and resistant strains.

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Article Synopsis
  • - Online STI testing is more cost-effective than traditional clinical testing and influences overall testing demand, prompting a need for broader system-level economic analysis to evaluate cost-effectiveness.
  • - Data from sexual health services in inner London showed that after two years of online services, 37% of STI tests were conducted online, increasing total diagnoses while slightly lowering the average cost per diagnosis.
  • - The positivity rate for online testing tends to be lower than for clinics, but varies by location; under certain conditions, online testing could reduce costs, suggesting a need for a combined approach to testing methods in clinics and online services.
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Background: Regular testing for sexually transmitted infections (STIs) is important to maintain sexual health. Self-sampling kits ordered online and delivered in the post may increase access, convenience, and cost-effectiveness. Sexual health economies may target limited resources more effectively by signposting users toward Web-based or face-to-face services according to clinical need.

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Article Synopsis
  • Zebrafish are becoming important for research due to their ability to help study various behavioral processes through both physical and computer trials.
  • A new data-driven model has been created to analyze zebrafish social interactions, focusing on their response mechanisms, which now incorporate dynamic speed changes along with turning movements.
  • This multi-agent model offers a fresh way to understand zebrafish behavior by directly using observations gathered from experiments, enhancing the study of their movement and interactions.
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Despite decades of development of formal tools for modelling legal knowledge and reasoning, the creation of a fully fledged legal decision support system remains challenging. Among those challenges, such system requires an enormous amount of commonsense knowledge to derive legal expertise. This paper describes the development of a negotiation decision support system (the Parenting Plan Support System or PPSS) to support parents in drafting an agreement (the parenting plan) for the exercise of parental custody of minor children after a divorce is granted.

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In this work, we develop a data-driven modelling framework to reproduce the locomotion of fish in a confined environment. Specifically, we highlight the primary characteristics of the motion of individual zebrafish (Danio rerio), and study how these can be suitably encapsulated within a mathematical framework utilising a limited number of calibrated model parameters. Using data captured from individual zebrafish via automated visual tracking, we develop a model using stochastic differential equations and describe fish as a self propelled particle moving in a plane.

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