Aneurysmal bone cyst of the skull: A case report.

The authors present a case report of a 14-year-old male with a single temporal scalp nodule. After imaging and surgical resection, the diagnosis of an aneurysmal bone cyst was made. Although aneurysmal bone cysts are benign, they tend to grow rapidly and cause subsequent complications.

Early Detection of Desiccation and Curettage Failure in the Treatment of Basal Cell Carcinoma.

Background/aims: Basal cell carcinoma (BCC) is a malignant neoplasm of keratinocytes. Electrodessication and curettage (ED&C) published cure rates vary widely, and the authors of this study are unaware of any previous literature which has attempted to rapidly identify treatment failures.

Objective: To identify BCC ED&C failures by histologically analyzing the fragments produced by the third round of curettage.

Treatment of recalcitrant herpes simplex virus with topical imiquimod.

Herpes simplex virus (HSV) is a common, easily transmissible virus. There is growing awareness of acyclovir-resistant HSV particularly among immunocompromised patients, which may be due to protracted treatments with guanosine analogues. Given the considerable morbidity associated with other classes of antiherpetic medications such as foscarnet (renal impairment, seizures) and cidofovir (renal impairment, neutropenia), imiquimod, a toll-like receptor agonist that enhances the innate immunologic responses against the virus, has been utilized in treating acyclovir-resistant HSV.

The necrolytic erythemas: a continuous spectrum?

The necrolytic erythemas is a group of disorders with similar histologic and clinical features. The objective of this case report is to present a patient with features of both necrolytic migratory erythema (NME) and necrolytic acral erythema (NAE). These 2 entities appear more likely to be on a spectrum caused by the same underlying process of abnormal liver function and glucagon metabolism.