Publications by authors named "Adam Twigg"

The goal of this quality improvement project was to improve internal medicine trainees' satisfaction with their formal teaching program. Initially, qualitative and quantitative data were collected from trainees, which demonstrated an overall negative attitude towards their teaching. Based on the feedback collected, changes were made to the teaching program, including switching to face-to-face teaching, using study leave in trainees' rosters to allow for higher attendance rates and planning subject-specific "teaching afternoons".

View Article and Find Full Text PDF

Aims: Pressurised metered-dose inhalers (MDIs) have a much higher carbon footprint than dry powder inhalers (DPIs). We aimed to describe variations of inhaler options in local adult asthma prescribing guidance.

Methods: We reviewed local clinical commissioning group (CCG) adult asthma prescribing guidance for primary care in England in 2019 and recorded DPI and MDI inclusion.

View Article and Find Full Text PDF

Sensitive serological testing is essential to estimate the proportion of the population exposed or infected with SARS-CoV-2, to guide booster vaccination and to select patients for treatment with anti-SARS-CoV-2 antibodies. The performance of serological tests is usually evaluated at 14-21 days post infection. This approach fails to take account of the important effect of time on test performance after infection or exposure has occurred.

View Article and Find Full Text PDF

Serological testing is used to quantify SARS-CoV-2 seroprevalence, guide booster vaccination and select patients for anti-SARS-CoV-2 antibodies therapy. However, our understanding of how serological tests perform as time passes after infection is limited. Four assays were compared in parallel: 1) the multiplexed spike, nucleoprotein and receptor binding domain Meso Scale Discovery (MSD) assay 2) the Roche Elecsys-Nucleoprotein assay (Roche-N) 3) the Roche Spike assay (Roche-S) and 4) the Abbott Nucleoprotein assay (Abbott-N) on serial positive monthly samples from hospital staff up to 200 days following infection as part of the Co-Stars study.

View Article and Find Full Text PDF