Publications by authors named "Adam Ruff"

Article Synopsis
  • SARS-CoV-2 infection can lead to long-term health issues known as post-acute sequelae of SARS-CoV-2 infection (PASC) or long COVID, which can manifest as ongoing or new symptoms after the initial infection.
  • The RECOVER-Adult study aims to better understand PASC by investigating its prevalence, symptoms, risk factors, and underlying biological mechanisms through a large cohort of nearly 15,000 adults.
  • Participants will provide ongoing data through questionnaires, physical examinations, and biological samples over several months, helping researchers gather critical insights into the complexities of long COVID.
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Importance: SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. Characterizing PASC requires analysis of prospectively and uniformly collected data from diverse uninfected and infected individuals.

Objective: To develop a definition of PASC using self-reported symptoms and describe PASC frequencies across cohorts, vaccination status, and number of infections.

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Cystoid macular edema (CME) is a major cause of central visual deterioration in retinitis pigmentosa. The exact reason for CME and its prognostic significance in this patient population is unknown. We seek to find clues to answer these questions by examining the anatomical correlations between retinal cysts and retinal morphometric parameters in a cohort of patients with retinitis pigmentosa and CME.

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Retinitis pigmentosa is the most common hereditary retinal disease. Dietary supplements, neuroprotective agents, cytokines, and lately, prosthetic devices, gene therapy, and optogenetics have been employed to slow down the retinal degeneration or improve light perception. Completing retinal circuitry by transplanting photoreceptors has always been an appealing idea in retinitis pigmentosa.

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In cases of significant prematurity, neonates born with eyelid fusion can undergo spontaneous eyelid disjunction. Here, the authors present such a case, along with ultrasound findings shortly before eyelid separation. All protected patient information extracted for this report was done so in accordance with the Health Insurance Portability and Accountability Act.

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