Publications by authors named "Adam Mohamad Bujang"
Int J Clin Pharm
August 2013
Article Synopsis
- This study investigates the prevalence and effect of CYP2C19 genetic variations on how Malaysian patients respond to clopidogrel, a common antiplatelet medication, particularly among those undergoing percutaneous coronary intervention.
- Conducted at Sarawak General Hospital, the research involved genotyping patients and assessing their platelet aggregation response to determine differences based on ethnicity and genetic profile.
- Results indicated that poor metabolisers, especially from the Chinese ethnic group, exhibited the highest resistance to clopidogrel, which highlights the potential for personalized medicine approaches based on genetic testing.
