Fatigue is a significant issue for individuals with interstitial lung disease (ILD), but research on this symptom is limited, hindering the development of treatment interventions.
The study aimed to evaluate the Fatigue Severity Scale (FSS) for measuring fatigue in ILD patients by testing its reliability and validity among 1,881 participants in the Pulmonary Fibrosis Foundation Patient Registry.
Findings indicate that the FSS has high internal consistency and moderate to strong correlations with certain patient-reported outcomes, but weak correlations with objective physiological measures, highlighting that fatigue is a crucial patient-centered outcome that is not effectively gauged by conventional disease metrics.