Publications by authors named "Adam Kroopnick"
Article Synopsis
Unbiased high-throughput sequencing (HTS) has enabled new insights into the diversity of agents implicated in central nervous system (CNS) infections. The addition of positive selection capture methods to HTS has enhanced the sensitivity while reducing sequencing costs and the complexity of bioinformatic analysis. Here we report the use of virus capture-based sequencing for vertebrate viruses (VirCapSeq-VERT) and bacterial capture sequencing (BacCapSeq) in investigating CNS infections.
View Article and Find Full Text PDFBackground: Unbiased high-throughput sequencing (HTS) has enabled new insights into the diversity of agents implicated in central nervous system (CNS) infections. The addition of positive selection capture methods to HTS has enhanced the sensitivity while reducing sequencing costs and complexity of bioinformatic analysis. Here we report the use of virus capture based sequencing for vertebrate viruses (VirCapSeq-VERT) and bacterial capture sequencing (BacCapSeq) in investigating CNS infections.
View Article and Find Full Text PDFArticle Synopsis
- The effectiveness of adjunctive corticosteroids in managing viral central nervous system (CNS) infections is not well understood, leading to confusion among clinicians about their use.
- Limited research exists on how steroids might help in these cases, making it challenging to determine their true benefits.
- The text explores steroid administration in three specific viral CNS diseases: varicella zoster virus (VZV), Powassan virus, and influenza A-linked acute necrotizing encephalopathy.