Synopsis of recent research by authors named "Adam Kirby"
- Adam Kirby's recent research focuses on the development and characterization of novel antiviral therapies and biologics to combat SARS-CoV-2 variants, particularly the Omicron strain, highlighting the efficacy of nanobodies and multivalent bicyclic peptides as new treatment modalities.
- His studies also explore the dynamics of SARS-CoV-2 in immunocompromised hosts and the implications for viral genome diversity and severe disease outcomes, using k18-hACE2 mouse models to understand the impact of antiviral treatments.
- Additionally, Kirby investigates the host-pathogen interactions in respiratory infections, elucidating the role of hypoxia inducible factors in modulating responses to viruses like respiratory syncytial virus, thereby advancing the understanding of disease mechanisms and potential therapeutic strategies.