Publications by authors named "Adam K Himes"
Article Synopsis
- The OmniaSecure defibrillation lead is a new, small-diameter lead aimed at improving targeted placement for better long-term performance in implantable cardioverter-defibrillators.
- The LEADR pivotal clinical trial involved 643 patients and showed that the lead was successfully placed in the correct position for 99.5% of participants, with a 97.5% success rate for defibrillation at implantation.
- The trial results indicated high safety and efficacy, with a 97.1% freedom from major complications and no lead fractures over an average follow-up of 12.7 months.
Segmented polyurethane multiblock polymers containing polydimethylsiloxane and polyether soft segments form tough and easily processed thermoplastic elastomers (PDMS-urethanes). Two commercially available examples, PurSil 35 (denoted as P35) and Elast-Eon E2A (denoted as E2A), were evaluated for abrasion and fatigue resistance after immersion in 85 °C buffered water for up to 80 weeks. We previously reported that water exposure in these experiments resulted in a molar mass reduction, where the kinetics of the hydrolysis reaction is supported by a straight forward Arrhenius analysis over a range of accelerated temperatures (37-85 °C).
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