Publications by authors named "Adam J Swigost"

Article Synopsis
  • A 73-year-old woman developed a quickly worsening, ulcerated growth on her eyelid that showed only slight improvement with infection treatment.
  • A biopsy confirmed it was primary cutaneous anaplastic large cell lymphoma (pcALCL), a rare disorder, but no other areas of the body were affected, suggesting a good prognosis.
  • Treatment usually involves surgical removal with clear margins; for more advanced cases, intravenous brentuximab vedotin is recommended.
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Amyloid precursor protein (APP) is widely expressed across many tissue and cell types. Proteolytic processing of the protein gives rise to a plethora of protein fragments with varied biological activities. Although a large amount of data has been generated describing the metabolism of the protein in neurons, its role in regulating the phenotype of other cells remains unclear.

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