Patent "Evergreening" of Medicine-Device Combination Products: A Global Perspective.

Background: Patenting medicine-delivery devices (inhalers and pens) is controversial when it extends market protections beyond that of the underlying therapeutic agent. We evaluated how common device patenting is, internationally.

Method: Using a product sample (n = 88) and an international patent database, we assessed the issue's scope.

Diets, Diseases, and Discourse: Lessons from COVID-19 for Trade in Wildlife, Public Health, and Food Systems Reform.

The COVID-19 pandemic has brought to light significant failures and fragilities in our food, health, and market systems. Concomitantly, it has emphasized the urgent need for a critical re-evaluation of many of the policies and practices that have created the conditions in which viral pathogens can spread. However, there are many factors that are complicating this process; among others, the uncertain, rapidly evolving, and often poorly reported science surrounding the virus' origins has contributed to a politically charged and often rancorous public debate, which is concerning insofar as the proliferation of divisive discourse may hinder efforts to address complex and collective concerns in a mutually cooperative manner.

Unmanned aerial vehicles reveal the impact of a total solar eclipse on the atmospheric surface layer.

We use unmanned aerial vehicles to interrogate the surface layer processes during a solar eclipse and gain a comprehensive look at the changes made to the atmospheric surface layer as a result of the rapid change of insolation. Measurements of the atmospheric surface layer structure made by the unmanned systems are connected to surface measurements to provide a holistic view of the impact of the eclipse on the near-surface behaviour, large-scale turbulent structures and small-scale turbulent dynamics. Different regimes of atmospheric surface layer behaviour were identified, with the most significant impact including the formation of a stable layer just after totality and evidence of Kelvin-Helmholtz waves appearing at the interface between this layer and the residual layer forming above it.

Frontier injustice: the American threat to Canada's drug supply.

"Import-from-Canada" strategies to address high prices for patented pharmaceuticals are gaining momentum in the United States. In the first two months of 2019 alone, five congressional bills incorporating such strategies were introduced; these bills have attracted bipartisan support across the fractious American political divide. At the same time, Canadian lawmakers continue their long-standing failure to take action in response to the looming threat of having Canada's drug supply siphoned off by its more powerful neighbour.

Design and Evaluation of Sensor Housing for Boundary Layer Profiling Using Multirotors.

Traditional configurations for mounting Temperature-Humidity (TH) sensors on multirotor Unmanned Aerial Systems (UASs) often suffer from insufficient radiation shielding, exposure to mixed and turbulent air from propellers, and inconsistent aspiration while situated in the wake of the UAS. Descent profiles using traditional methods are unreliable (when compared to an ascent profile) due to the turbulent mixing of air by the UAS while descending into that flow field. Consequently, atmospheric boundary layer profiles that rely on such configurations are bias-prone and unreliable in certain flight patterns (such as descent).

Upstream solutions for price-gouging on critical generic medicines.

Exorbitant price increases for critical off-patent medicines have received considerable media attention in recent months, leading to an investigation by the U.S. Senate.

Screening and Treating UN Peacekeepers to Prevent the Introduction of Artemisinin-Resistant Malaria into Africa.

Stan Houston and Adam Houston highlight how deployment of UN peacekeepers has the potential to introduce artemisinin-resistant malaria into Africa.