Publications by authors named "Adam Grzela"
Is Component-Specific Antibody Testing Sufficient to Replace the Oral Food Challenge in the Diagnostics of Peanut-Sensitized Children? A Proof-of-Concept Study.
Klementyna Łyżwa Klaudia Prasek Anna Krupa-Łaska Joanna Zielińska Alicja Krejner-Bienias Adam Grzela Tomasz Grzela Katarzyna Grzela
Int J Mol Sci
July 2024
Article Synopsis
- Peanut allergy poses a serious risk of anaphylaxis, which might be mitigated through oral immunotherapy based on patient food challenges and antibody assessments against key peanut proteins.
- A study with 74 peanut-sensitized children explored the links between specific antibodies, food challenge results, skin tests, and other factors, dividing participants into two groups based on challenge responses.
- The findings indicated distinct differences in skin test results and antibody levels between the groups; while antibody-based predictions had some statistical relevance, they did not accurately predict severe symptoms or anaphylaxis risk, suggesting more research is needed for clinical application.