Publications by authors named "Adam Globerman"
Article Synopsis
- The study aims to assess how the size of the primary tumor in T3 N0-3M0 supraglottic cancers affects overall survival (OS) and disease-free survival (DFS) for patients treated with intensity-modulated radiotherapy (IMRT).
- This retrospective cohort analysis involved 239 patients from Canadian cancer centers, measuring tumor volume via imaging and employing survival analysis methods.
- Results indicate that larger primary tumor volume correlates with worse OS and DFS, suggesting that patients with significant tumor sizes might benefit more from surgical intervention like laryngectomy followed by radiotherapy.*
Association of Primary Tumor Volume With Survival in Patients With T3 Glottic Cancer Treated With Radiotherapy: A Study of the Canadian Head & Neck Collaborative Research Initiative.
JAMA Otolaryngol Head Neck Surg
February 2023
Importance: The association of primary tumor volume with outcomes in T3 glottic cancers treated with radiotherapy with concurrent chemotherapy remains unclear, with some evidence suggesting worse locoregional control in larger tumors.
Objective: To evaluate the association of primary tumor volume with oncologic outcomes in patients with T3 N0-N3 M0 glottic cancer treated with primary (chemo)radiotherapy in a large multi-institutional study.
Design, Setting, And Participants: This multi-institutional retrospective cohort study involved 7 Canadian cancer centers from 2002 to 2018.
A young man presented to the emergency department reporting he had been recently shot in the face and chest with an unknown weapon. Initial physical examination only found bruising by the left hemimandible, but CT angiography of the thorax revealed a BB in the right ventricle. A subsequent CT angiography of the head and neck showed no major arterial injury but noted stranding and irregularity of the left facial vein directly deep to the injury site.
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