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Publications by authors named "Adam D Pierce"

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Synopsis of recent research by authors named "Adam D Pierce"

  • - Adam D. Pierce's research primarily focuses on the role of calcium-binding proteins S100B and S100A1 in malignant melanoma, uncovering their impacts on key signaling pathways and potential therapeutic targets for cancer treatment.
  • - Findings highlight the regulatory mechanisms by which S100B modulates interleukin-6 production and its effects on p53 tumor suppressor functionality, alongside the discovery of novel small-molecule inhibitors that restore p53 activity in melanoma cells.
  • - Additionally, Pierce's studies explore the influence of RUNX2 transcriptional activity in endothelial cells under hyperglycemic conditions, implicating it in angiogenesis and cancer progression, illustrating a connection between metabolism and tumor biology.

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