Ectopic molar in the maxillary sinus precipitating a mucocele: a case report and literature review.

Ectopic teeth are rarely found in the maxillary sinus. When they are, they represent an anomaly of odontogenic development that is generally associated with odontogenic cysts, trauma, or idiopathic etiology. Although affected patients are often asymptomatic, documented morbidities include sinus disease that is often refractory to treatment.

Topical application of mitomycin C to the middle ear is ototoxic in the gerbil.

Hypothesis: Mitomycin C is ototoxic when applied topically to the structures of the middle ear.

Background: Mitomycin C is a topically applied medication widely used in a variety of surgical procedures to prevent excessive scar tissue formation. Its safety for use during otologic procedures has not been fully evaluated.

Effects of gap junction uncoupling in the gerbil cochlea.

Objective: To gain insight into molecular and cellular mechanisms regulating cochlear potassium (K+) recycling, including the possible effects of mutations in the gene, which encodes the gap junction protein connexin 26. Intercellular K+ flux was manipulated in vivo by infusion of the gap junction uncoupler proadifen (SKF-525A) into perilymph. Functional and structural alterations induced by gap junction blockade were assessed by electrophysiological and morphologic analysis.