Objective: In the treatment of bilateral cleft lip and palate (BCLP) patients, there is discussion about the management of the position of the premaxilla. This literature analysis summarises the literature on managing this condition.
Materials And Methods: A PubMed, Embase and Cochrane Library search was conducted resulting in 4465 articles which were screened on title and abstract.
Objectives: Can a synthetic bone substitute be used to repair the alveolar cleft to bypass donor site morbidity as well as to shorten the operating time? In earlier experimental studies, micro-structured beta-tricalcium phosphate (β-TCP) provided similar bone healing when compared with grafting with iliac crest bone. This justifies the clinical evaluation of this bone substitute in the human alveolar cleft situation.
Design: Prospective clinical study.
Objectives: The purpose of this study was to evaluate the use of synthetic bone graft material as a filling material at the mandibular symphysis donor site of autologous bone in children.
Materials And Methods: A blinded patient group comprised 20 patients with unilateral (UCLP) or bilateral (BCLP) cleft of lip and palate, all with an indication for alveolar cleft repair. The study took the form of a prospective randomized clinical trial.
Cleft Palate Craniofac J
November 2011
Objective: The aim of this study in goats was to test the hypothesis that a novel synthetic bone substitute beta tricalcium phosphate (β-TCP) can work as well as autologous bone harvested from the iliac crest for grafting and repair of alveolar clefts.
Design: Ten adult Dutch milk goats (Capra hircus) were used in a split-mouth study design.
Main Outcome Measures: Volumetric histologic assessment of new bone formation and radiographic measurement of orthodontic movement of teeth in a formerly created alveolar cleft.
Proc Natl Acad Sci U S A
August 2010
Biomaterials can be endowed with biologically instructive properties by changing basic parameters such as elasticity and surface texture. However, translation from in vitro proof of concept to clinical application is largely missing. Porous calcium phosphate ceramics are used to treat small bone defects but in general do not induce stem cell differentiation, which is essential for regenerating large bone defects.
View Article and Find Full Text PDFObjective: To analyze orthodontic treatment results following mandibular symphysis bone grafting and postoperative orthodontic treatment.
Design: Randomized selection of 75 patients out of 308 with unilateral cleft of lip, alveolus, and palate, operated upon according to protocol between 1990 and 2008 in the Wilhelmina Children's Hospital, Utrecht, The Netherlands.
Main Outcome Measure: Goslon Yardstick rating changes of dental arch relationship.
© LitMetric 2025. All rights reserved.