Impact of prompt gamma emission of Sc on quantification in preclinical and clinical PET systems.

Sc is an increasingly investigated positron emitter for use in positron emission tomography (PET) imaging. However, Sc is a non-pure positron emitter, since prompt photons are co-emitted during the decay process. This study investigates coincidence energy spectra of Sc and its impact on PET quantification on a preclinical and clinical PET system in comparison with F.