Preoperative Physical Therapy is Associated With Decreased Length of Stay and Improved Postoperative Mobility in Patients With Sarcopenia Undergoing Adult Spinal Deformity Surgery.

Study Design: Retrospective cohort study.

Objective: To determine the relationship between preoperative physical therapy (PT) and postoperative mobility, adverse events (AEs), and length of stay (LOS) among patients with low normalized total psoas area (NTPA) undergoing adult spinal deformity (ASD) surgery.

Background: Sarcopenia, as defined by low NTPA, has been shown to predict poor perioperative outcomes of ASD surgery.

Geometric Mismatch Promotes Anatomic Repair in Periorbital Bony Defects in Skeletally Mature Yucatan Minipigs.

Porous tissue-engineered 3D-printed scaffolds are a compelling alternative to autografts for the treatment of large periorbital bone defects. Matching the defect-specific geometry has long been considered an optimal strategy to restore pre-injury anatomy. However, studies in large animal models have revealed that biomaterial-induced bone formation largely occurs around the scaffold periphery.

Awareness, knowledge, and factors that influenced the uptake of screening tests for prostate cancer among men aged 40 and older in Ido-Ekiti, Ekiti State, Nigeria.

Background: Despite being the second most common and deadliest cancer in males, prostate cancer could go unnoticed in the early stages. Prevention programs have been set in place to help in the early detection and reduction of mortality rates in developed countries.

Objective: The aim of this study was to determine awareness, knowledge, and the uptake of prostate cancer screening tests.

A delayed diagnosis of congenital midline cervical cleft.

Congenital midline cervical cleft (CMCC) is an extremely rare anomaly of the neck that typically presents in the neonatal period as a thin suprasternal vertical band of erythematous skin with a nipple-like projection. We present the management of this uncommon and rarely described entity in a 9-year-old girl.

Point-of-care treatment of geometrically complex midfacial critical-sized bone defects with 3D-Printed scaffolds and autologous stromal vascular fraction.

Critical-sized midfacial bone defects present a unique clinical challenge due to their complex three-dimensional shapes and intimate associations with sensory organs. To address this challenge, a point-of-care treatment strategy for functional, long-term regeneration of 2 cm full-thickness segmental defects in the zygomatic arches of Yucatan minipigs is evaluated. A digital workflow is used to 3D-print anatomically precise, porous, biodegradable scaffolds from clinical-grade poly-ε-caprolactone and decellularized bone composites.

Cervical spine computed tomography motion artifact mimicking spine injury in a patient with severe head injury.

Background: Craniocervical CT scan is an essential part of the routine evaluation of patient with moderate and severe head injury to rule out associated cervical spine injury. Computed tomography motion artifacts can affect clinical decision making. The aim of this report is to emphasize that motion artifact still exists despite advance in technology and this can pose clinical challenge.

Paratesticular fibrous pseudotumour in a 26-year-old Nigerian man: A case report.

Introduction And Importance: Benign fibroblastic proliferation located within the scrotum are uncommon. They are also identified as fibrous pseudotumour and usually arise from the paratesticular region. Their pathogenesis is unknown.

Effects of Single-Dose Versus Hypofractionated Focused Radiation on Vertebral Body Structure and Biomechanical Integrity: Development of a Rabbit Radiation-Induced Vertebral Compression Fracture Model.

Purpose: Vertebral compression fracture is a common complication of spinal stereotactic body radiation therapy. Development of an in vivo model is crucial to fully understand how focal radiation treatment affects vertebral integrity and biology at various dose fractionation regimens. We present a clinically relevant animal model to analyze the effects of localized, high-dose radiation on vertebral microstructure and mechanical integrity.

Design and implementation of a crossflow turbine for Pico hydropower electricity generation.

This study covered the design, implementation and performance evaluation of a crossflow turbine at various nozzle positions. The chosen blade material was analyzed using ANSYS for stress and deformation degree under the impact of hydraulic jets to ascertain its suitability while in operation. The shaft was analyzed under static and dynamic conditions using ANSYS in order to ensure a non-plastic deformation of the shaft at both conditions.

Fabrication of cellulose nanofiber/polypyrrole/polyvinylpyrrolidone aerogels with box-Behnken design for optimal electrical conductivity.

A sponge-like conductive aerogel has been fabricated comprising spherical nanoparticles of polypyrrole and jelly polyvinylpyrrolidone on the surface of cellulose nanofibrils defibrillated from water hyacinth fibres. Box-Behnken response surface methodology was used to optimize the aerogel's electrical conductivity for understanding its relationship with the synthesis conditions. Morphological and microstructural results showed that water hyacinth cellulose nanofibrils has a rough topography and an average height of 5 nm.

Heparin-Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF-BB to Adipose-Derived Stem Cells in Tissue Engineered Bone Grafts.

Adipose-derived stem cells (ASCs) are a promising cell source for regenerating critical-sized craniofacial bone defects, but their clinical use is limited due to the supraphysiological levels of bone morphogenetic protein-2 required to induce bone formation in large grafts. It has been recently reported that platelet-derived growth factor-BB (PDGF) directly enhances the osteogenesis of ASCs when applied at physiological concentrations. In this study, a biomimetic delivery system that tethers PDGF to decellularized bone matrix (DCB) is developed to enhance osteogenic signaling in bone grafts by colocalizing PDGF-extracellular matrix cues.

Analysis of the dynamic energy flow associated with phagocytosis of bacteria.

This paper treats the phenomenon of phagocytosis from the flow of energy point of view. Considerable efforts have been made towards elucidating the subject of phagocytosis in other fields of learning, but little has been said about the mechanical work that is done during phagocytosis. Phagocytosis without doubt is an interaction that involves the flow of energy.