Groundwater for drinking and industrial purposes: A study of water stability and human health risk assessment from black sand mineral rich coastal region of Kerala, India.

Tempero-spatial analysis of groundwater to disseminate the level of drinking water quality and industrial suitability to meet the developmental requirement of a region is a significant area of research. Accordingly, groundwater quality and geochemical interactions prevailed in a black sand mineral rich coastal village is systematically presented in appraisal of drinking and industrial uses for economic engineering purposes. The study area focused is Alappad village, Kollam, Kerala, India has numerous ecological features in a sustainable perspective.

The hidden impact of seafood processing on coastal aquifers: Hydrogeochemistry and water quality assessment.

Seafood processing industries play a crucial role in meeting global food demands; however, their consequences on groundwater quality are a growing concern. The study fills the existing knowledge gap among the shallow aquifers of the Southwest coast of India by conducting a thorough assessment of the hydrogeochemical alterations caused by the release of wastewater and waste by-products related to seafood processing operations. The methodology involves a multi-faceted approach, encompassing field sampling, hydro-chemical modelling, and statistical validation.

Groundwater chemistry and entropy weighted water quality index of tsunami affected and ecologically sensitive coastal region of India.

Quality groundwater is the most essential prerequisite for the better livelihood of the coastal villages and a vital resource for a safe living. Seawater interaction and coastal inundation modify hydro geochemical cycles leading to gross utility as a challenge. Poor quality water intake causes diseases and seriously affects human health.

Antiproliferative effects of dried Moringa oleifera leaf extract on human Wharton's Jelly mesenchymal stem cells.

Mesenchymal stem cells (MSCs) have seen an elevated use in clinical works like regenerative medicine. Its potential therapeutic properties increases when used in tandem with complementary agents like bio-based materials. Therefore, the present study is the first to investigate the cytotoxicity of a highly valued medicinal plant, Moringa oleifera, on human Wharton's Jelly mesenchymal stem cells (hWJMSCs) and its effects on the cells' gene expression when used as a pre-treatment agent in vitro.

Integration of heterogeneous photocatalysis and persulfate based oxidation using TiO-reduced graphene oxide for water decontamination and disinfection.

Advanced oxidation processes (AOPs) which involve the generation of highly reactive free radicals have been considered as a promising technology for the decontamination of water from chemical and bacterial pollutants. In this study, integration of two major AOPs ., heterogeneous photocatalysis involving TiO-reduced graphene oxide (T-RGO) nanocomposite and activated persulfate (PS) based oxidation was attempted to remove diclofenac (DCF), a frequently detected pharmaceutical contaminant in water.

Integration of coagulation-flocculation and heterogeneous photocatalysis for the treatment of pulp and paper mill effluent.

A two-step process involving coagulation-flocculation followed by solar photocatalysis - based Advanced Oxidation Process (AOP) using TiO-Reduced Graphene Oxide (TRGO) nanocomposite as catalyst has been employed for the treatment of pulp and paper mill effluent. As the effluent is loaded with a high amount of organics with initial chemical oxygen demand (COD) as high as 3516, a pre-treatment is required before applying photocatalytic treatment. Coagulation-flocculation was identified as an effective pre-treatment strategy.

Prevalence of diabetes and cardiovascular risk factors in middle-class urban participants in India.

Objectives: To determine the prevalence of diabetes and awareness, treatment and control of cardiovascular risk factors in population-based participants in India.

Methods: A study was conducted in 11 cities in different regions of India using cluster sampling. Participants were evaluated for demographic, biophysical, and biochemical risk factors.

High prevalence of metabolic syndrome among urban subjects in India: a multisite study.

Objective: Metabolic syndrome is an important cardiovascular risk factor. To determine its prevalence among urban subjects in India we performed a multisite study.

Methods: The study was performed at eleven cities using cluster sampling.

Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: a cross sectional study.

Objective: To determine levels of cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians.

Methods: Population based 6123 subjects (men 3388) were evaluated. Mean±1SD of various cholesterol lipoproteins (total, HDL, LDL and non-HDL cholesterol) and triglycerides were reported.

Normotension, prehypertension, and hypertension in urban middle-class subjects in India: prevalence, awareness, treatment, and control.

Objective: We conducted a multisite study to determine the prevalence and determinants of normotension, prehypertension, and hypertension, and awareness, treatment, and control of hypertension among urban middle-class subjects in India.

Methods: We evaluated 6,106 middle-class urban subjects (men 3,371; women, 2,735; response rate, 62%) in 11 cities for sociodemographic and biological factors. The subjects were classified as having normotension (BP < 120/80), prehypertension (BP 120-139/80-89), and hypertension (documented or BP ≥ 140/90).

Molecular dynamics study of anhydrous lamellar structures of synthetic glycolipids: effects of chain branching and disaccharide headgroup.

Glycolipids form materials of considerable potential for a wide range of surfactant and thin film applications. Understanding the effect of glycolipid covalent structure on the properties of their thermotropic and lyotropic assemblies is a key step toward rational design of new glycolipid-based materials. Here, we perform molecular dynamics simulations of anhydrous bilayers of dodecyl β-maltoside, dodecyl β-cellobioside, dodecyl β-isomaltoside, and a C(12)C(10) branched β-maltoside.

Association of educational, occupational and socioeconomic status with cardiovascular risk factors in Asian Indians: a cross-sectional study.

Background: To determine correlation of multiple parameters of socioeconomic status with cardiovascular risk factors in India.

Methods: The study was performed at eleven cities using cluster sampling. Subjects (n = 6198, men 3426, women 2772) were evaluated for socioeconomic, demographic, biophysical and biochemical factors.

Short-term mortality and complications in ST elevation myocardial infarction--the Heart Hospital experience.

The mortality rate of acute myocardial infarction has declined considerably in the past three decades. In view of paucity of literature from different centres from India on this issue, the present study was undertaken to determine the in-hospital mortality with acute ST segment elevation myocardial infarction presenting to a tertiary care cardiac centre in India. Consecutive patients (n=862) with the diagnosis of acute ST segment elevation myocardial infarction admitted in Heart Hospital, Patna between June 2003 and July 2006 were included in this study.

Takayasu's disease presenting with pain chest, prolonged pyrexia and pleural effusion.

Takayasu's disease (TD) is a diffuse arteriopathy recognised by various names viz. Takayasu Arteritis, Takayasu's Disease, Takayasu Syndrome, Pulseless Disease, Non-specific Aortoarteritis, Reversed Coarctation, Aortic Arch Syndrome, Aortitis Syndrome, Young Female Arteritis, Idiopathic Arteritis and Martorell Syndrome. Though described about a century ago and with many eponyms, TD yet remains a challenging problem regarding etiopathogenesis, clinical presentation and management.

Association of major modifiable risk factors among patients with coronary artery disease--a retrospective analysis.

Background: The relative importance of various risk factors varies in different regions of India. This was a retrospective study of patients with recently diagnosed coronary artery disease to assess four major risk factors: dyslipidemia, hypertension, smoking and diabetes.

Material And Methods: A total of 5748 patients (4952 males, 796 females) with recently diagnosed coronary artery disease were analysed from the records of Heart Hospital along with 8103 controls (6092 males and 2011 females).

A study of lipid levels in uncomplicated hypertension.

A number of risk factors for coronary artery disease are known to be present in hypertensive patients, the most important being hyperlipidemia. An analysis of the lipid profiles of 3,182 uncomplicated non-diabetic patients (2,425 males, 757 females) who attended two institutions of Patna city between 1992-1998 was conducted alongwith 4,131 controls. Mean total cholesterol was slightly higher (but statistically significant; p < or = 0.

Echocardiographic detection of cardiac involvement in chronic renal failure.

The aim of this work was to determine the incidence of occult cardiac involvement in chronic renal failure (CRF). 50 adult patients (42 male, 8 female) were subjected to echocardiography (by both M-mode and 2D methods). Pericardial effusion was detected in 15 patients (30%), 2 patients (4%) had dilated left ventricles with poor contractility and sluggish interventricular septum (IVS) movement, suggesting cardiomyopathy.

Comparison of regimens of treatment with sodium stibogluconate in kala-azar.

One hundred and twenty six patients with kala-azar (visceral leishmaniasis) were allocated at random to one of two groups for treatment with sodium stibogluconate. One group was treated for 20 days; in the other group the patients were assessed after 20 days' treatment and treatment was continued if necessary. Both groups were followed up for six months.