Publications by authors named "Achamma Chandy"

Study Question: Is there a difference in dietary patterns among subfertile South Asian women undergoing frozen embryo transfer (FET)?

Summary Answer: Significant regional differences in dietary pattern exist among subfertile South Asian women undergoing FET.

What Is Known Already: Preconception consumption of certain food groups or adopting specific dietary patterns, such as the 'Mediterranean diet', and its level of adherence have been shown to enhance the odds of achieving a successful pregnancy in women undergoing ART. However, differences in geographic location, individual preference, cultural beliefs and local availability contribute to such dietary choices.

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Article Synopsis
  • A study assessed the knowledge and attitudes of subfertile couples in the Indian subcontinent about what to do with excess cryopreserved embryos after assisted reproductive technology (ART) treatments.
  • Out of 87 couples interviewed, 38% were unaware of their options, with most preferring to donate embryos to other infertile couples rather than discontinue storage.
  • The study found that demographics like age, education, and income didn't significantly affect couples' decisions on embryo donation, emphasizing a strong inclination towards donating instead of abandonment.
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Aim: The aim of the study was to compare the perinatal outcomes between singletons following vanishing twin phenomenon and singletons arising from initial single gestational sac following assisted reproductive technology (ART) treatment.

Setting And Design: This was a retrospective cohort study.

Materials And Methods: A retrospective cohort study included analysis of all singleton births following ART over a period of 7 years (January 2010 -December 2016).

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Objective: The main purpose of this study was to determine the prevalence of vitamin D deficiency in infertile women with polycystic ovarian syndrome (PCOS) and to explore the association of hypovitaminosis D with metabolic syndrome in women with PCOS.

Study Design: A prospective observational study was conducted in a tertiary care, infertility centre from March 2016 to March 2017. The primary outcome was estimation of the prevalence of vitamin D deficiency in infertile PCOS women.

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Background: Assessment of ovarian reserve before an fertilization cycle (IVF) is one among the many factors that predicts a successful cycle. Individualized protocol based on ovarian reserve is designed to optimize the pregnancy outcome without compromising the patient safety. Although authors have shown that anti-Mullerian hormone-tailored (AMH) protocols have reduced the treatment burden and improved pregnancy rates, a few others have questioned its efficacy.

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Aim: The aim of the study was to measure patient's satisfaction level and acceptance of conscious sedation as a method of pain relief following transvaginal oocyte retrieval (TVOR) during assisted reproduction technology treatment. We also evaluated the factors that may influence the efficacy of conscious sedation method.

Setting And Design: A prospective cross-sectional study.

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Background: The purpose of the study was to evaluate the role of Progesterone/ Estradiol (P4/E2) ratio as a predictive tool for clinical pregnancy in ART cycles with a premature progesterone rise of >1.5 ng/ml on the day of human chorionic gonadotropin (hCG) trigger.

Methods: Retrospective analysis was done on 569 fresh embryo transfer cycles from January 2011 to December 2012 at the infertility unit of a tertiary care hospital.

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Objectives: The overwhelming numbers of twins following assisted reproductive technology (ART) are dichorionic twins, but monochorionic twins account for around 0.9% of post ART pregnancies. The data for post ART-monochorionic pregnancy outcomes are scarce due to the rarity of this condition.

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Objectives: The literature regarding clinical outcomes following day 5/6 vitrified warmed blastocysts transfer has been conflicting. We decided to evaluate and compare the clinical outcomes following vitrified warmed day 5/6 blastocyst transfer using a solid surface vitrification protocol with fresh blastocyst transfers.

Settings: University teaching hospital.

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Objective: The aim of the present study was to evaluate the prevalence of metabolic syndrome in women with polycystic ovary syndrome (PCOS).

Setting: Infertility clinic in a tertiary care hospital.

Study Design: A prospective cross-sectional study.

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In 36 women with polycystic ovary syndrome and clomiphene citrate resistance, letrozole, an aromatase inhibitor, statistically significantly increased the ovulation rate by 33.3% in the treatment group, indicating that letrozole can be used as an effective and simple alternate ovulation-inducing agent in these women.

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This randomized controlled trial compared spontaneous ovulation versus hCG-triggered ovulation in anovulatory women treated with clomiphene citrate. No statistically significant differences were observed between the two groups in terms of ovulation and pregnancy rates.

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Background: Male factor abnormality is the cause of infertility in about 20%-40% of infertile couples. Assisted reproduction with intracytoplasmic sperm injection is the only treatment option for severe forms of andrological infertility.

Methods: We retrospectively analysed patients who had had intracytoplasmic sperm injection for male factor infertility.

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