Idelalisib and Rituximab in 17p Deletion-Positive Splenic Marginal Zone Lymphoma.

Splenic marginal zone lymphoma (SMZL) is a rare indolent B-cell malignancy involving the spleen and bone marrow. Various cytogenetic abnormalities with prognostic value have been identified in SMZL. Complexity of karyotype, 14q aberrations, and deletions have been found to be poor prognostic indicators.

Late recurrence of gastric cancer with isolated brain metastasis.

A 70-year-old woman presented to our clinic in 2007 after an evaluation for dysphagia revealed a poorly differentiated adenocarcinoma of the gastroesophogeal junction. Workup for metastatic disease was negative at presentation. She had a complete response to treatment, which was completed in November 2007.