Psychopharmacotherapy of Pica-?

There is little evidence for psychopharmacotherapy in pica. A few studies reported some benefit from the use of SSRIs, atypical antipsychotics and methylphenidate. That said, evidence to deploy these agents remains, at large, flimsy.

Effect of Polymer/Nano-Clay Coatings on the Performance of Concrete with High-Content Supplementary Cementitious Materials under Harsh Exposures.

In recent concrete research, a novel category of coatings has emerged: polymers/nanoparticles blends. The efficacy of such coatings warrants extensive examination across various concrete mixtures, particularly those incorporating high-volume supplementary cementitious materials (SCMs) to mitigate carbon footprints, an industry imperative. This study used three vulnerable concrete mixtures to assess the effectiveness of ethyl silicate and high-molecular-weight methyl methacrylate blended with 2.

COVID-19 vaccine hesitancy among healthcare workers in Arab Countries: A systematic review and meta-analysis.

Background: Vaccine hesitancy is a major obstacle to the large efforts made by governments and health organizations toward achieving successful COVID-19 vaccination programs. Healthcare worker's (HCWs) acceptance or refusal of the vaccine is an influencing factor to the attitudes of their patients and general population. This study aimed to report the acceptance rates for COVID-19 vaccines among HCWs in Arab countries and identify key factors driving the attitudes of HCWs in the Arab world toward vaccines.

Impaction bone grafting for contained acetabular defects in total hip arthroplasty.

Background: Acetabular bone loss is a technical challenge in total hip arthroplasty (THA). This study sought to report the functional and radiological results of acetabular reconstruction using impaction bone grafting (IBG) in patients with acetabular bone deficiency undergoing primary or revision THA.

Methods: In this prospective study, full history taking, preoperative clinical and radiological evaluation, and preoperative planning and templating were performed.

Apoptotic and histopathological defects enhanced by titanium dioxide nanoparticles in male mice after short-term exposure.

Titanium dioxide nanoparticles (TiONPs) are commercially utilized in diverse fields. Therefore, the current study investigated the apoptotic and histopathological defects that were caused in male mice following intraperitoneal (i.p) injection of TiONPs for 28 days.

Low-Dose Risperidone for an Autistic Child with Comorbid ARFID and Misophonia.

Avoidant/Restrictive Food Intake Disorder and misophonia seem to be overrepresented in autism spectrum disorder. Literature is mute on psychopharmacotherapy in these complex presentations. Here, authors report on a challenging case of low-functioning ASD child with comorbid ARFID and misophonia that responded favorably to a low-dose risperidone.

Limitations of imaging screening tests in the detection of incomplete uterine septum or arcuate uterine anomaly.

Objectives: To determine the detection rates of hysterosalpingogram (HSG), transvaginal 2D ultrasound (TV 2D US), transvaginal 3D ultrasound (TV 3D US) in diagnosing of incomplete uterine septum (IUS) and significant arcuate uterine anomaly (AUA).

Methods: This retrospective cohort study included patients with infertility or recurrent pregnancy loss (516) that were found to have IUS (317) or significant AUA (199) on diagnostic hysteroscopy (DHS). We compared the detection rate of the various radiological tests in all patients with documented IUS or AUA on DHS.

Perfecting hysterosalpingography: Limitations to the use of disposable balloon catheter and its solution.

Objective: To revive the use of the Kahn Uterine Trigger Cannula to overcome limitations associated with technical difficulties during hysterosalpingography (HSG) using the disposable balloon HSG catheter.

Method: A case series was conducted of 17 patients who encountered technically difficult or incomplete HSG study while using a disposable HSG balloon catheter, also leading to false-positive findings. Nine patients underwent a repeat HSG using a Kahn Uterine Trigger Cannula (Group 1).

Minimally invasive management of juvenile cystic adenomyoma: report of three cases.

Background: Juvenile cystic adenomyosis (JCA) represents a rare form of focal adenomyosis in young women.

Objectives: To determine safety and effectiveness of minimally invasive surgery (MIS for JCA).

Materials And Methods: Three patients aged 16-30 years old presented with chronic pelvic pain [2016 - 2019].

Depression: A Gut "Microbiome" Feeling!

Burgeoning body of evidence from neuroscience is pouring in highlighting a potential association between gut microbiota with the pathophysiology of depression and anxiety. Manipulation of gut microbiota may be then useful to decode this role and to provide novel therapeutics for major depressive disorder (MDD), developing microbiota-related biomarkers to stratify patients at risk and to delineate more homogeneous biotypes of MDD.

Morin alleviates fructose-induced metabolic syndrome in rats ameliorating oxidative stress, inflammatory and fibrotic markers.

Metabolic syndrome (MBS) is a widespread disease that has strongly related to unhealthy diet and low physical activity, which initiate more serious conditions such as obesity, cardiovascular diseases and type 2 diabetes mellitus. This study aimed to examine the therapeutic effects of morin, as one of the flavonoids constituents, which widely exists in many herbs and fruits, against some metabolic and hepatic manifestations observed in MBS rats and the feasible related mechanisms. MBS was induced in rats by high fructose diet feeding for 12 weeks.

Safety and efficacy of hysteroscopic resection of uterine leiomyoma embedded at the base of a uterine septum.

Background: To determine the safety and efficacy of hysteroscopic resection of uterine leiomyoma embedded at the base of a uterine septum.

Methods: This case series included 11 patients with infertility or recurrent pregnancy loss who were found to have a uterine septum (one septate and 10 sub-septate) and a uterine leiomyoma embedded at the base of the uterine septum. All patients underwent a hysteroscopic division of the uterine septum and hysteroscopic resection of the uterine leiomyoma.

Recombinant Anti-Müllerian Hormone (rAMH) for Stalling In Vitro Granulosa Cell Replication.

To investigate whether recombinant AMH (rAMH) is able to decrease cellular proliferation/apoptosis in luteinized granulosa cells (GCs) through hormonal regulation, a primary culture of GCs was established from GCs obtained at time of oocyte retrieval from follicular fluid of 3 patients. Cells were seeded in well cell culture plates at a density of 100,000 cells/well in medium and treated with rAMH 20 ng/ml (rAMH group), or phosphate-buffered saline (PBS-control group), for 24 h. Total RNA was extracted from all cells, followed by cDNA synthesis and real-time RT-PCR to quantify the expression levels of AMH, AMH-R2, FSH-R, inhibin B, cell proliferation (Ki67), and apoptosis (Caspase 3).

Safety and efficacy of two techniques of temporary ovarian suspension to the anterior abdominal wall after operative laparoscopy.

Background: This retrospective study compares the safety and efficacy of temporary ovarian suspension (TOS) to the anterior abdominal wall using absorbable versus non-absorbable suture after operative laparoscopy to elevate the ovaries away from the ovarian fossa to reduce postoperative adhesion development.

Methods: Patients (n=152) underwent TOS to the anterior abdominal wall at the conclusion of surgery between 1998 and 2017. One hundred forty-two patients underwent operative laparoscopy for advanced stages of endometriosis (93.

The impact of single versus double blastocyst transfer on pregnancy outcomes: A prospective, randomized control trial.

Objective: To determine if elective single blastocyst transfer (e-SBT) compromises pregnancy outcomes compared to double blastocyst transfer (DBT) in patients with favorable reproductive potential.

Methods: This Randomized Control Trial included 50 patients with SBT (Group 1) and 50 patients with DBT (Group 2). All women were <35 years and had favorable reproductive potential.

The place for prophylactic cerclage in the infertile patient with established cervical incompetence who conceived twins after septum reduction.

Introduction: It is well known that cervical incompetence and associated preterm birth confers greater morbidity and mortality on birth outcomes, with an additional increased risk of cervical incompetence in higher order gestations. While the pathophysiology of cervical incompetence has yet to be elucidated, research has identified risk factors and assessed outcomes of numerous interventions. Cervical cerclage has been shown, in certain situations involving singleton pregnancies, to improve outcomes.

Pediatric Foley Catheter Placement After Operative Hysteroscopy Does Not Cause Ascending Infection.

Study Objective: To determine the incidence of postoperative ascending infection without antibiotics with the use of a pediatric Foley catheter (PFC) after operative hysteroscopy for intrauterine pathology.

Design: Retrospective case series (Canadian Task Force classification III).

Setting: University-affiliated outpatient medical center.

A Modified Technique of Temporary Suspension of the Ovary to the Anterior Abdominal Wall.

Study Objective: To demonstrate a modified technique of temporary suspension of the ovary to the fascia of the anterior abdominal wall after operative laparoscopy for advanced stage-endometriosis to reduce postoperative adhesion formation.

Design: Video illustrating this modified technique of ovarian suspension (Canadian Task Force classification III).

Setting: A previous study described a technique of temporary suspension of the ovary to the abdominal wall using nylon suture [1].