Publications by authors named "Abusamra Khawla"
No study has investigated the length of time it takes to diagnose multiple sclerosis (MS) or neuromyelitis optic spectrum disorder (NMOSD, aquaporin 4 antibody disease or myelin oligodendrocyte glycoprotein antibody disease, MOGAD) following the onset of de novo optic neuritis (ON). Minimizing the time between ON and downstream diagnoses needs urgency since early diagnosis equals early treatment. The time elapsed from ON to a subsequent diagnosis of MS/NMOSD was estimated through analysis of retrospective data collected from the Axon Registry (AR) of the American Academy of Neurology (AAN) and from the University of Kentucky (UK), Lexington.
View Article and Find Full Text PDFNeuromyelitis Optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system (CNS) where aquaporin-4 water channels are the antigenic target of the disease. The spectrum of the disease involves regions of the CNS where the water channel is widely expressed including the spinal cord, the optic nerve, dorsal medulla, brainstem, and thalamus/hypothalamus. Management of NMOSD includes acute as well as long term treatment.
View Article and Find Full Text PDFPurpose: To assess long-term effectiveness of rituximab therapy for refractory noninfectious uveitis affecting the posterior segment.
Methods: Retrospective case series. Patients diagnosed with recalcitrant noninfectious posterior uveitis who were treated with rituximab intravenous infusions between 2010 and 2015 were included.
Purpose: To calculate the rate and timing of conversion from ocular myasthenia gravis to generalized myasthenia gravis.
Design: Retrospective multicenter analysis.
Subjects: Patients included in the study were diagnosed with ocular myasthenia gravis without the presence of generalized disease at onset.