Serum selenium levels of the very low birth weight premature newborn infants with bronchopulmonary dysplasia.

Background: The selenium (Se) is an essential trace element that has a critical role in synthesis and activity of a number of selenoproteins with protective properties against free radical damage. This study was conducted to detect the serum Se concentration in very low birth weight (VLBW) preterm infants and its association with bronchopulmonary dysplasia (BPD).

Materials And Methods: Cord blood Se concentration was determined in 54 neonates with gestation age 30 week or less.

Determination of selenium in serum samples of preterm newborn infants with bronchopulmonary dysplasia using a validated hydride generation system.

Bronchopulmonary dysplasia (BPD), also known as chronic lung disease, is one of the most challenging complications in premature newborn infants. Selenium plays a role in antioxidant system by protecting cell membranes and neutralizing the deleterious effects of free radicals. The aim of this study was to determine the relationship between selenium concentration and incidence of bronchopulmonary dysplasia using a validated analytical method.