Publications by authors named "Abul Hasan Shadali Abdul Khader"

Ghosal hematodiaphyseal dysplasia (GHDD) is a rare autosomal recessive disorder characterized by increased bone density involving diaphyses of long bones and defective hematopoiesis. It is due to biallelic variants in the TBXAS1 (OMIM*274180) gene, which encodes for thromboxane synthase. We present a rare case of a middle-aged woman who presented with chronic anemia and bone pain.

View Article and Find Full Text PDF

Multiple cranial nerve palsies frequently accompany hypoglossal nerve palsy, potentially indicating malignancy, such as lymphoma, nasopharyngeal carcinoma, or metastases. However, when solely the hypoglossal nerve is affected, the causes may involve Chiari malformation, arachnoid cyst, or infectious mononucleosis, suggesting a positive prognosis. Craniocervical junction tuberculosis (TB), is an uncommon cause of isolated hypoglossal nerve palsy and has been reported infrequently in the literature.

View Article and Find Full Text PDF

Celecoxib, a selective COX-2 inhibitor, and non-selective anti-inflammatory drug, is commonly prescribed as the first-line analgesic for osteoarthritis, rheumatoid arthritis, and certain acute pain cases. It is mainly preferred for its lower risk of gastrointestinal adverse effects. However, it also carries risks, including renal and liver toxicity, anaphylaxis, and Stevens-Johnson syndrome.

View Article and Find Full Text PDF

Background: Prior systematic reviews addressing the impact of diet on cancer outcomes have focused on specific dietary interventions. In this systematic review, we assessed all randomized controlled trials (RCTs) investigating dietary interventions for cancer patients, examining the range of interventions, endpoints, patient populations, and results.

Methods: This systematic review identified all RCTs conducted before January 2023 testing dietary interventions in patients with cancer.

View Article and Find Full Text PDF

Cardiovascular diseases (CVDs) pose a significant burden on global health. Developing effective diagnostic, therapeutic, and prognostic indicators for CVDs is critical. This narrative review explores the role of select non-coding RNAs (ncRNAs) and provides an in-depth exploration of the roles of miRNAs, lncRNAs, and circRNAs in different aspects of CVDs, offering insights into their mechanisms and potential clinical implications.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the prevalence and outcomes of pulmonary embolism (PE) in patients with sickle cell disease (SCD), finding that out of 405,020 patients with PE, only 1,504 (0.4%) had SCD.
  • - SCD patients were predominantly female and Black, had lower comorbidity rates, but experienced higher in-hospital mortality (41%) and lower rates of advanced treatments like catheter-directed thrombolysis and mechanical thrombectomy.
  • - The findings stress the need for healthcare providers to be more vigilant in diagnosing PE in patients with SCD to potentially lower their high in-hospital mortality rates.
View Article and Find Full Text PDF