Background: We present the case of a 6-y-old boy who was diagnosed with sensory processing disorder with developmental language and learning delay. He was treated successfully with diet and high-dose biotin along with other nutrient support that resulted in resolution of abnormal sensory behaviors and improvement in language and learning.
Case/intervention: The child was diagnosed with a presumed biotin deficiency from organic acids testing which revealed markers that reflected biotin deficiency despite supplementation with 300 mcg daily (AI = 12 mcg/d).