Royal Jelly Exerts a Potent Anti-Obesity Effect in Rats by Activating Lipolysis and Suppressing Adipogenesis.

This study examined the anti-obesity effect of royal jelly (RJ) in rats fed with a high-fat diet by targeting the major pathways involved in adipogenesis and lipolysis. In addition, it examined whether this effect is AMPK-dependent. Five groups of adult male albino rats were used ( = 6 each as 1); the control rats were fed with a normal diet (2.

Ultrasonic-enhanced photocatalysis through piezoelectric and cavitation effects for lignin depolymerization.

Although a promising method for lignin depolymerization, photocatalysis faces the challenge of low efficiency. In this study, MoS/ZnO heterojunction catalysts, endowed with piezocatalysis and photocatalytic capabilities, were crafted through Zn ion intercalation for the depolymerization of phenoxyphenylethanol (PP-ol) and alkali lignin. Then, the synergistic interplay between ultrasonic-induced piezoelectric fields and heterojunctions was analyzed.

Saudi date cultivars' seed extracts inhibit developing hepatic steatosis in rats fed a high-fat diet.

This research aim was to assess the impact of the seed extracts of the date cultivars (Qatara, Barhi, and Ruthana) on rat's liver steatosis, oxidative stress, and inflammation triggered by feeding a high-fat diet (HFD). The experimental design was based on random partitioning into two groups; one that received the standard diet and another that received the HFD diet. The HFD rats were orally administered Lipitor or date seed extracts at 300 or 600 mg/kg/day for 4 weeks.

alleviates diabetic nephropathy in a rat model by attenuating glucose levels, oxidative stress, and inflammation with concomitant suppression of TGF-β1.

In this research, the treatment of diabetic nephropathy in rats induced by streptozotocin with whole-plant aqueous extract was examined, and the mechanism of action was proposed. Adult male rats were grouped into: control, , T1DM, and T1DM + -treated groups. For 8 weeks, S was given to rats at a final dose of 250 mg/kg.

Activation of AMPK Entails the Protective Effect of Royal Jelly against High-Fat-Diet-Induced Hyperglycemia, Hyperlipidemia, and Non-Alcoholic Fatty Liver Disease in Rats.

This study examined the mechanism underlying the protective effect of royal jelly (RJ) against high-fat-diet (HFD)-mediated non-alcoholic liver disease (NAFLD) in rats. Adult male rats were divided into five groups (n = 8 each): control fed a standard diet, control + RJ (300 mg/kg), HFD, HFD + RJ (300 mg/kg), and HFD + RJ + CC (0.2 mg/kg).

Laccase-catalyzed lignin depolymerization in deep eutectic solvents: challenges and prospects.

Lignin has enormous potential as a renewable feedstock for depolymerizing to numerous high-value chemicals. However, lignin depolymerization is challenging owing to its recalcitrant, heterogenous, and limited water-soluble nature. From the standpoint of environmental friendliness and sustainability, enzymatic depolymerization of lignin is of great significance.

Phytochemicals-Loaded Iron Oxide Nanoparticles Induce Cytotoxicity and Stimulate Apoptosis in MCF-7 Human Breast Cancer Cells.

The present study aimed to synthesize iron oxide nanoparticles loaded with quinine and alkaloids-rich (Peruvian bark) stem bark extract, and further evaluate their cytotoxic effect and apoptosis mechanisms in MCF-7 breast cancer cells. Nanoparticles were prepared by biological reduction of iron oxide with extract, using the green synthesis method. The nanoparticles were characterized by XRD, FT-IR, and UV-vis spectroscopy and transmission electron microscopy (TEM).

Synthesis of (Jujube) Root Methanol Extract Loaded Functionalized Silver Nanoparticle (ZS-Ag-NPs); Physiochemical Characterization and Effect of ZS-Ag-NPs on Adipocyte Maturation, Adipokine and Vascular Smooth Muscle Cell Interaction.

In this research, a simple, green approach was employed to synthesize silver nanoparticles with the aid of (L.) methanol root extract, which can act as a reducing, capping agent to treat obesity and inflammation. Globally, (Jujube) root is used in traditional therapy as a lipolysis promoter.

Effects of sonication on the in vitro digestibility and structural properties of buckwheat protein isolates.

The present work investigated the effects of sonication at different amplitudes and durations on the in vitro digestibility of buckwheat protein isolates (BPIs). The conformation, particle size and microstructures of the BPIs were also studied to explicate the possible mechanisms of the sonication-induced changes. The results showed that sonication conditions of 20 kHz, pulsed on-time 10 s, off-time 5 s, amplitude of 60% and duration of 10 min (SA6T10) improved the digestibility of BPIs from 41.