[Evaluation of hypotensive and antiischemic effects of a combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients suffering from coronary artery disease with arterial hypertension].

The hypotensive and antiischemic activity of combined therapy with dihydropyridine group (amlodipine) and non-dihydropyridine group (verapamil retard) calcium antagonists (CA) as well as tolerance to this therapy were studied in 43 patients suffering from coronary heart disease (CAD) with II-III functional class exertional angina and II degree essential hypertension during 24 weeks. Twenty-four-hour ECG and blood pressure (BP) monitoring and Doppler EchoCG were done. The combination of amlodipine and verapamil retard in different day doses made it possible to achieve target BP levels in 86% of cases, improved circadian BP pattern and decreased left ventricular myocardial mass index (18.

[Determining the extent of gastric cancer by the thermographic method].

In an analysis of findings of thermographic examinations of the anterior abdominal wall in 167 patients with gastric cancer four types of thermograms were established: the 1st type of thermographic picture with focal hyperthermia in the epigastric area and left hypochondrium was characteristic of gastric tumors not exceeding the limits of the organ. Carcinomatosis of the abdomen is characterized by the 2nd type of the thermographic picture. The third and fourth types characterized by intensive infrared radiation along all the anterior abdominal wall indicate mostly inoperable tumoral process.

[Clinical characteristics of radiation sickness with radiation exposure of different parts of the human body].

The clinical picture of radiation sickness of 139 radiological patients exposed to local irradiation of the head, chest and stomach with efficient doses of 210 rad was examined. It was found that at fractionated local irradiations the clinical symptom-complex of radiation sickness was identical to that seen as a result of total-body irradiation. During head irradiation the major symptom was headache and during stomach irradiation nausea.

[Biological effects in the partial irradiation of dogs with high-energy protons].

Biological effects of irradiation of the head, chest and stomach of dogs with 250 Mev protons at a dose of 600 rad were investigated. Due to irradiation all the animals developed radiation sickness of moderate severity. A comparative study of the peripheral blood and immunobiological reactivity of the dogs showed that an exposure of the head exerted the least effect; an exposure of the chest and stomach had a very similar effect.

[Hematopoiesis in dogs irradiated with protons in lethal doses with screening of the bone marrow].

The paper presents the results of a 6-year investigation of hemopoiesis of dogs which were exposed to double irradiations (with a 1.5-month interval) with protons at a dose of 350 rad when different parts of the body (head, chest, abdomen, pelvis) were shielded. Throughout the entire period the dogs showed moderate leucopenia and by the end of the investigation insignificant anemia.