Publications by authors named "Abram Soliman"
Introduction: Careful adverse event assessment and management are important when prescribing immune checkpoint inhibitors (ICIs) to cancer patients. Iatrogenic Sjogren's syndrome is a relatively rare immune-related adverse event (irAEs) that affects the moisture-producing glands.
Methods: We describe a series of four patients who developed Sjogren's syndrome while being treated with ICIs at a community cancer center in Southern California, USA (1/1/2017-12/31/2023).
Article Synopsis
- The text discusses a case of oral lichenoid drug eruption (LDE) in a 75-year-old woman undergoing treatment with the EGFR inhibitor osimertinib for lung cancer.
- After 24 months of treatment, she developed painful oral lesions, which were biopsied and confirmed as LDE, with a moderate likelihood linking it to osimertinib.
- Treatment involved a mouthwash and dietary adjustments, leading to symptom improvement, while highlighting the importance of monitoring and awareness of potential side effects like LDE from osimertinib.
Introduction: Oxaliplatin has become the mainstay of treatment for many cancers, but its use can be accompanied by unusual side effects.
Case Report: We describe herein a 74-year-old patient with pancreatic cancer who developed severe motor weakness affecting lower extremities after starting treatment with oxaliplatin on three separate occasions. Our patient also experienced slurred speech, with decreased ability to phonate and word-finding difficulty.
Cycle-dependent eosinophilia due to adjuvant nivolumab for malignant melanoma.
J Oncol Pharm Pract
July 2023
Introduction: Immune checkpoint inhibitors (ICIs) have been widely used in the contemporary anticancer armamentarium. However, new side effects due to these agents have continued to emerge.
Case Report: We describe herein a 71-year-old patient who received nivolumab as adjuvant therapy for malignant melanoma of the skin.