Publications by authors named "Abrahem Sayed"
Tyrosine kinase inhibitors (TKIs) serve to inhibit the phosphorylation cascade that usually leads to abnormal processes such as vascular leakage and tumorigenesis. Within retinal diseases specifically, dysregulation of the vascular endothelial growth factor receptor tyrosine kinases can lead to age-related macular degeneration and diabetic macular edema. These diseases have a growing prevalence and are leading causes of vision loss.
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- * It uses vorolanib, which blocks all forms of VEGF to reduce abnormal blood vessel growth and leakage in the eye.
- * The Durasert delivery system allows for a steady release of vorolanib directly into the eye, leading to less frequent doctor visits and a safer, more convenient treatment option.