Publications by authors named "Abraham Mains"
Article Synopsis
- Scientists created a way to study how genes control aging by looking at a "crowd" of information and using complex math.
- They discovered new genes important for living longer and how these genes work together, especially those tied to health like insulin signaling.
- The researchers found a new gene helper that works with an important aging gene, showing that their method could help speed up finding new health discoveries for people too.
In this contribution, we describe a multi-omics systems biology study of the metabolic changes that occur during aging in . Sampling several time points from young adulthood until early old age, our study covers the full duration of aging and include transcriptomics, and targeted MS-based metabolomics. In order to focus on the metabolic changes due to age we used two strains that are metabolically close to wild-type, yet are conditionally non-reproductive.
View Article and Find Full Text PDFMetabolism is one of the attributes of life and supplies energy and building blocks to organisms. Therefore, understanding metabolism is crucial for the understanding of complex biological phenomena. Despite having been in the focus of research for centuries, our picture of metabolism is still incomplete.
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