Background: Increasing evidence suggests that adipose tissue contains mesenchymal stem cells (MSC) that possess the ability to transdifferentiate into other cell types including hepatocytes, similar to bone marrow-derived stem cells. The existence of precommitted cells in the MSC population may explain transdifferentiation.
Aims: Our aim was to identify a population of putative hepatocyte-like precursor cells in human adipose tissue.
Scand J Plast Reconstr Surg Hand Surg
September 2004
Most of the techniques that have been suggested for closure of sacral pressure sores use musculo-cutaneous flaps. We report our experience in three patients using the SpaceMaker balloon dissector. The dissector was inserted into the subgluteal maximus muscle plane to expand the muscle and overlying skin, thereby forming bilateral sliding and tension-free musculocutaneous flaps.
View Article and Find Full Text PDFThe pectoralis major advancement flap is currently the most popular technique for reconstruction of the anterior chest in patients with sternotomy wounds. Recently, the SpaceMaker balloon was introduced for rapid expansion of the pectoralis major muscle intraoperatively. The aim of the present study was to investigate the biomechanical and histologic effects of this expansion technique in a rat model.
View Article and Find Full Text PDFBackground: Large defects of the lower lip represent a challenge to the reconstructive surgeon. The reconstructed lip should be sensate, retain muscle function, allow sufficient mouth opening for dentures, and have an acceptable aesthetic appearance. Many surgical techniques for lower lip reconstruction have been reported.
View Article and Find Full Text PDFPrevention of hernia or bulge of the abdominal wall after TRAM breast reconstruction has been a challenge for the reconstruction surgeon. Different techniques have been described to avoid this complication. The use of anterior rectus abdominis sheath (ARAS) for the repair of various abdominal wall hernias has been well described in the literature and is the basis of the authors' technique.
View Article and Find Full Text PDFThe incidence of cutaneous malignant melanoma is increasing constantly. The most accurate prognostic factor of primary melanoma is thickness of the lesion according to Breslow. Information and screening campaigns for early diagnosis of melanoma are based on the assumption that tumor thickness is the consequence of a delay in diagnosis.
View Article and Find Full Text PDFAesthetic Plast Surg
July 2002
Hypertrophic scars cause great discomfort to the patient and pose a challenge for the reconstructive surgeon. This is particularly true in the facial area. Optimal function and aesthetic appearance are the main goals of reconstruction.
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