The TRIANGLE operation is a surgical method aimed at improving outcomes for patients with resectable pancreatic ductal adenocarcinoma (PDAC) by removing all tissues within a specific triangular area related to major blood vessels.
A retrospective study compared outcomes for patients undergoing pancreaticoduodenectomy (PD) with or without the TRIANGLE procedure from January 2017 to April 2023, finding that the recurrence rate was significantly lower in the TRIANGLE group.
Results indicate that the TRIANGLE operation is safe and could lower local recurrence rates and potentially enhance survival in patients receiving adequate adjuvant chemotherapy.
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis largely due to its association with perineural invasion and increased neural density.
The review highlights the significant role of Schwann cells (SCs) in the tumor-neural interface, affecting tumor growth and the surrounding environment.
It calls for further research into SCs' roles in PDAC, aiming to improve understanding and explore potential therapeutic strategies targeting these cells.
The TRIANGLE operation is beneficial for pancreatic cancer patients, but the presence of specific vessels in the Heidelberg triangle can affect surgical safety, especially during laparoscopic pancreaticoduodenectomy (LPD).
A study analyzed 3D CT scans of 184 patients, identifying two vessel types in the Heidelberg triangle: Type I (no vessels) and Type II (with named vessels).
Findings indicated that patients with Type II had significantly higher intraoperative blood loss and more lymph nodes examined than those with Type I, highlighting the need for careful preoperative planning to enhance safety during the procedure.