Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series.

Background: Tracheobronchopathia osteochondroplastica (TO) is a rare condition of unknown etiology. TO is characterized by submucosal nodules, with or without calcifications, protruding in the anterolateral walls of the trachea and proximal bronchi. The objective of this study was to describe TO features and associated comorbidities in a series of patients.

β-Arrestin inhibition induces autophagy, apoptosis, G0/G1 cell cycle arrest in agonist-activated V2R receptor in breast cancer cells.

Non-visual arrestins (β-arrestins) are endocytic proteins that mediate agonist-activated GPCRs internalization and signaling pathways in an independent manner. The involvement of β-arrestins in cancer invasion and metastasis is increasingly reported. So, it is hypothesized that inhibition of β-arrestins may diminish the survival chances of cancer cells.

Researchers' And Medical Student' Experience in Reference Management Software in a Low-Income Country.

Introduction: Although the use of Reference Management Software (RMS) is increasing in developed countries, they seem to be unknown and less used in low-income countries.

Aim: To discover the major trends in the use of RMS among researchers and Ph.D.

The relationship between the fraction of exhaled nitric oxide and the level of asthma control.

Background: The evaluation of asthma control, based on symptoms and risk factors for exacerbation does not provide information about airway inflammation, reflected by fractional exhaled nitric oxide (FeNO). The impact of FeNO in the evaluation of asthma control has not been well recognized. The purpose of this study was to evaluate the contribution of FeNO measurement in the assessment of asthma control.

Determining the optimal time to assess the reversibility of airway obstruction.

Context: The optimal time to interpret bronchodilator reversibility remains controversial. This time may affect a positive diagnosis and manage asthma and chronic obstructive pulmonary disease (COPD).

Aims: We sought to document the time when maximum respiratory function is reached after inhalation of salbutamol and to define the optimal time of bronchodilator response to assess the reversibility or non reversibility of airway obstruction.

Evaluation of an interactive teaching method in the teaching of Pulmonology.

Introduction: For several years, interactive teaching has proved its effectiveness in learning. At the Faculty of Medicine of Tunis (FMT), the interactive sessions are sessions of clarification, illustration, application, and participation (CIAP).

Aim: To evaluate pneumology CIAP session in the acquisition of learning by first-year students of the second cycle of medical studies (SCMS1).

Management of combat-related facial injuries.

Introduction: Combat-related facial injuries involve various lesions of the mouth, the eye sockets and the facial bones. The goal of this study is to precise the particularities of these affections and their therapeutic management.

Methods: A retrospective study was performed about 56 cases of combat-related facial injuries over a period of 5 years (2010 - 2014).

Acute acoustic trauma: how to manage and how to prevent?

Introduction: The consequence of an exposure to intense sounds can be a temporary or permanent hearing loss and even with a rapid therapeutic management, severe sensorineural sequelae may persist.

Methods: the authors report a retrospective study about 64 patients followed for an acute acoustic trauma during a period of 8 years (2006 to 2013). For all the cases, a clinical examination associated to a pure-tone audiometry was conducted.

Impact of obstructive sleep apnea on the right ventricle.

Background: Right ventricular (RV) involvement in obstructive sleep apnea syndrome (OAS) is controversial. The aim of this study was to determine a correlation between echocardiographic parameters of RV function and severity of OSA assessed by the apnea- hypopnea index (AHI).

Methods: Sixty patients with suspected OSA were enrolled.

Impact of obstructive sleep apnea on the right ventricle.

Background: Right ventricular (RV) involvement in obstructive sleep apnea syndrome (OAS) is controversial. The aim of this study was to determine a correlation between echocardiographic parameters of RV function and severity of OSA assessed by the apnea- hypopnea index (AHI).

Methods: Sixty patients with suspected OSA were enrolled.

A spiritual sleepiness scale: the Friday prayer.

Background: Excessive daytime sleepiness (EDS) affects 5% to 20% of the population and is involved in a large number of traffic accidents. EDS is a major symptom in sleep disorders, especially obstructive sleep apnea syndrome (OSA). The daytime sleepiness is evaluated subjectively using scales and questionnaires based on perception.

Orbital metastasis revealing an undifferenciated Carcinoma of nasopharyngeal type: a case report.

The evolution of the undifferentiated carcinoma of the nasopharynx (NPC) is marked by the occurrence of regional or distant metastasis. We report a rare observation of bilateral orbital metastasis of NPC. Clinical symptoms were ocular proptosis, blurred vision and eye redness.