Publications by authors named "Aboubecrin Sedhigh Haidara"
ACS Infect Dis
November 2021
Article Synopsis
- The cultivation of the malaria parasite has spurred research aimed at understanding it better and developing effective drug treatments.
- Current drug discovery efforts face challenges due to a lack of systems for cultivating its asexual blood stages, which are necessary for testing antimalarial drugs.
- The study improved the culture conditions for the malaria parasite, allowing for the screening of compounds like artemether and chloroquine to assess their antimalarial effectiveness.
J Antimicrob Chemother
July 2021
Article Synopsis
- The study assesses how susceptible Plasmodium malariae is to various current and experimental antimalarial drugs.
- Results show reduced effectiveness of traditional drugs like chloroquine, lumefantrine, and artemether against P. malariae, while piperaquine and newer drugs like GNF179 and KDU691 were found to be highly effective.
- The findings suggest the need to reconsider the use of standard treatments for P. malariae infections and highlight the promising potential of newer drug candidates.
