DMTMM-mediated amidation of sodium alginate in aqueous solutions: pH-dependent efficiency of conjugation.

DMTMM-mediated amidation of sodium alginate is one of the methods used for the chemical modification of alginate with amines. However, there is a limited understanding of how the reaction conditions, particularly the pH value, influence the conjugation efficiency (CE) and the resulting degree of substitution (DS). In this study, we investigated the effect of the pH during the reaction, focusing on both neutral and weakly basic conditions, using water and buffer as solvents.

pH-sensitive aminated chitosan/carboxymethyl cellulose/aminated graphene oxide coated composite microbeads for efficient encapsulation and sustained release of 5-fluorouracil.

The application of smart pH-sensitive carriers has become an ideal choice for administering drugs with desired release profiles. Although pH-sensitive microbeads offer distinct benefits for delivering anticancer drugs orally, they encounter drawbacks, including low encapsulation efficiency, weak mechanical stability, biocompatibility concerns, and the risk of abrupt release. This study focuses on developing pH-sensitive coated composite microbeads for effective encapsulation and sustained release of 5-fluorouracil (5-FU).

Postmodification with Polycations Enhances Key Properties of Alginate-Based Multicomponent Microcapsules.

Postmodification of alginate-based microspheres with polyelectrolytes (PEs) is commonly used in the cell encapsulation field to control microsphere stability and permeability. However, little is known about how different applied PEs shape the microsphere morphology and properties, particularly . Here, we addressed this question using model multicomponent alginate-based microcapsules postmodified with PEs of different charge and structure.

Sulfonic acid-functionalized k-carrageenan/Cr-based metal-organic framework: An efficient and recyclable catalyst for fructose conversion to 5-hydroxymethylfurfural.

A novel bio-based catalyst was developed by in-situ forming Chromium(III) (Cr)-based metal-organic framework, MIL-101(Cr), in the presence of k-carrageenan (k-Car) and followed by a post-synthetic modification to introduce additional -SOH functional groups into the composite structure of k-Car/MIL-101(Cr). Different analyses were conducted to confirm the successful catalyst formation. The catalyst performance was evaluated in the solid acid catalyzed dehydration of fructose to 5-hydroxymethylfurfural.

3D-Printed Cyclodextrin Polymer Encapsulated Wells-Dawson: A Novel Catalyst for Knoevenagel Condensation Reactions.

In the pursuit of enhancing the catalytic potential of the Wells-Dawson (WD) polyoxometalate (POM) while addressing its solubility challenges, this study focuses on devising a sustainable catalyst that operates effectively in aqueous environments. Leveraging cyclodextrin (CD) polymer chemistry in conjunction with 3D printing technology, a CD nanosponge, recognized for its interaction with POMs and molecular shuttle attributes, is synthesized as a scaffold for WD immobilization. Through integration into a 3D-printed monolith framework, the supported WD species becomes embedded within the catalyst structure, facilitating its application.

Bioadhesive and Injectable Hydrogels and Their Correlation with Mesenchymal Stem Cells Differentiation for Cartilage Repair: A Mini-Review.

Injectable bioadhesive hydrogels, known for their capacity to carry substances and adaptability in processing, offer great potential across various biomedical applications. They are especially promising in minimally invasive stem cell-based therapies for treating cartilage damage. This approach harnesses readily available mesenchymal stem cells (MSCs) to differentiate into chondrocytes for cartilage regeneration.

Biosynthesis of ternary NiCoFeO nanoflowers: investigating their 3D structure and potential use in gene delivery.

Multicomponent nanoparticle systems are known for their varied properties and functions, and have shown potential as gene nanocarriers. This study aims to synthesize and characterize ternary nickel-cobalt-ferrite (NiCoFeO) nanoparticles with the potential to serve as gene nanocarriers for cancer/gene therapy. The biogenic nanocarriers were prepared using a simple and eco-friendly method following green chemistry principles.

Cyclodextrin Host-Guest Recognition in Glucose-Monitoring Sensors.

Diabetes mellitus is a prevalent chronic health condition that has caused millions of deaths worldwide. Monitoring blood glucose levels is crucial in diabetes management, aiding in clinical decision making and reducing the incidence of hypoglycemic episodes, thereby decreasing morbidity and mortality rates. Despite advancements in glucose monitoring (GM), the development of noninvasive, rapid, accurate, sensitive, selective, and stable systems for continuous monitoring remains a challenge.

Palladated Cyclodextrin Nanosponge-Alginate Dual Bead as an Efficient Catalyst for Hydrogenation of Nitroarenes in Aqueous Solution.

In this study, we present a novel composite material consisting of β-cyclodextrin nanosponge and sodium alginate, used as a support for the immobilization of palladium (Pd) nanoparticles. The composite alginate-cyclodextrin nanosponge beads were prepared, taking advantage of the 3D polymeric network and β-cyclodextrin cavity of the nanosponge. These beads exhibited excellent encapsulation capabilities for hydrophobic substrates, allowing their transfer in aqueous media.

Matricaria chamomilla essential oil-loaded hybrid electrospun nanofibers based on polycaprolactone/sulfonated chitosan/ZIF-8 nanoparticles for wound healing acceleration.

Recently, developing antibacterial wound dressings based on biomaterials display good biocompatibility and the potential to accelerate wound healing. For this aim, we prepared eco-friendly and biodegradable nanofibers (NFs) based on N-(3-sulfopropyl)chitosan/ poly (ε-caprolactone) incorporated by zeolite imidazolate framework-8 nanoparticles (ZIF-8 NPs) and chamomile essential oil (MCEO) via the electrospinning technique for their efficacy as wound dressing scaffolds. Fabricated NFs were characterized and studied for their structural, morphological, mechanical, hydrophilic, and thermal stability properties.

Novel photo and bio-active greyish-black cotton fabric through air- and nitrogen- carbonized zinc-based MOF for developing durable functional textiles.

This study explores the potential of using the carbonization of Zn-based metal-organic frameworks (Zn-MOF-5) under N and air to modify zinc oxide (ZnO) nanoparticle for the production of various photo and bio-active greyish-black cotton fabrics. The MOF-derived ZnO under N demonstrated a significantly higher specific surface area (259 mg) compared to ZnO (12 mg) and MOF-derived ZnO under air (41.6 m g).

Improved cotton fabrics properties using zinc oxide-based nanomaterials: A review.

Zinc oxide nanoparticles (ZnO NPs) have gained significant attention in the textile industry for their ability to enhance the physicochemical properties of fabrics. In recent years, there has been a growing focus on the development of ZnO-based nanomaterials and their applications for cotton and other fabrics. This review paper provides an overview of the synthesis and diverse applications of ZnO-based nanomaterials for textile fabrics, including protection against UV irradiation, bacteria, fungi, microwave, electromagnetic radiation, water, and fire.

Thermoplastic starch/bentonite clay nanocomposite reinforced with vitamin B: Physicochemical characteristics and release behavior.

This study presents the development and characterization of a nanocomposite material, consisting of thermoplastic starch (TPS) reinforced with bentonite clay (BC) and encapsulated with vitamin B (VB). The research is motivated by the potential of TPS as a renewable and biodegradable substitute for petroleum-based materials in the biopolymer industry. The effects of VB on the physicochemical properties of TPS/BC films, including mechanical and thermal properties, water uptake, and weight loss in water, were investigated.

Chitosan bead containing metal-organic framework encapsulated heteropolyacid as an efficient catalyst for cascade condensation reaction.

Using cyclodextrin and chitosan that are bio-based compounds, a novel bi-functional catalytic composite is designed, in which metal-organic framework encapsulated phosphomolybdic acid was incorporated in a dual chitosan-cyclodextrin nanosponge bead. The composite was characterized via XRD, TGA, ICP, BET, NH-TPD, FTIR, FE-SEM/EDS, elemental mapping analysis and its catalytic activity was examined in alcohol oxidation and cascade alcohol oxidation-Knoevenagel condensation reaction. It was found that the designed catalyst that possess both acidic feature and redox potential could promote both reactions in aqueous media at 55 °C and various substrates with different electronic features could tolerate the aforementioned reactions to furnish the products in 75-95% yield.

Interleukin-12 Plasmid DNA Delivery by -[(2-Hydroxy-3-trimethylammonium)propyl]chitosan-Based Nanoparticles.

Cationic polysaccharides are capable of forming polyplexes with nucleic acids and are considered promising polymeric gene carriers. The objective of this study was to evaluate the transfection efficiency and cytotoxicity of -[(2-hydroxy-3-trimethylammonium)propyl] chitosan salt (HTCS), a quaternary ammonium derivative of chitosan (CS), which benefits from non-ionizable positive charges. In this work, HTCS with a full quaternization of amino groups and a molar mass of 130,000 g·mol was synthesized to use for delivery of a plasmid encoding the interleukin-12 (IL-12) gene.

Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties.

In this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using Sambucus nigra L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM).

Thermoplastic Starch-Based Composite Reinforced by Conductive Filler Networks: Physical Properties and Electrical Conductivity Changes during Cyclic Deformation.

Conductive polymer composites (CPC) from renewable resources exhibit many interesting characteristics due to their biodegradability and conductivity changes under mechanical, thermal, chemical, or electrical stress. This study is focused on investigating the physical properties of electroconductive thermoplastic starch (TPS)-based composites and changes in electroconductive paths during cyclic deformation. TPS-based composites filled with various carbon black (CB) contents were prepared through melt processing.

Facile synthesis of Zn-based metal-organic framework in the presence of carboxymethyl cellulose: A safe carrier for ibuprofen.

Fabrication of porous materials with a high surface area affords a great interest to achieve a system with a prolonged drug release manner. In this context, the subject of this work is to describe a novel green one-pot synthesis route for the growth of metal-organic framework (MOF) from zinc metal (Zn) and 1, 4-benzene dicarboxylic acid (BDC) in the vicinity of the carboxymethyl cellulose (CMC), which homogeneously confined in the biopolymeric chains. The synthesized Zn (BDC)@CMC was characterized and confirmed using different analyses.

In situ dual crosslinking strategy to improve the physico-chemical properties of thermoplastic starch.

This study is focused on enhancing the stability of mechanical and chemical properties of thermoplastic starch (TPS) by dual crosslinking strategy through melt processing conditions. The dually crosslinked TPS was prepared by in situ reaction of starch, glycerol, and epichlorohydrin (ECH), resulting in both noncovalent and covalent bond formation. The TPS was characterized by tensile testing, dynamic mechanical analysis (DMTA), rheology, and solubility in water.

A versatile β-cyclodextrin and N-heterocyclic palladium complex bi-functionalized iron oxide nanoadsorbent for water treatment.

By industrialization, management of water resources is known as one of the most challenging issues for human society due to the presence of various contaminants such as oil, azo dyes, and micropollutants in water. The treatment of wastewaters containing more than one type of pollutants via a single-step process cannot be performed by a simple adsorption process. In this study, by combining the advantages of superparamagnetic iron oxide, carboxymethyl-β-cyclodextrin polymer, and N-heterocyclic palladium complex, a versatile bi-functionalized iron oxide nanoadsorbent [FeO@CM-β-CDP@Tet-Pd] was fabricated for the capture of toxic dyes in wastewater.

Ultrasound-assisted synthesis of MIL-88(Fe) coordinated to carboxymethyl cellulose fibers: A safe carrier for highly sustained release of tetracycline.

For stopping long-time harmful bacterial infection, designing a drug carrier with a highly prolonged release profile is a promising approach that is of interest to different biomedical areas. The subject of this work is to synthesis a novel carrier system through coordination of MIL-88(Fe) to carboxymethyl cellulose (CMC) for enhancing interaction between drug and carrier. We established an ultrasound-assisted synthetic method for in situ synthesis of MIL-88(Fe) in the presence of CMC resulting in CMC/MIL-88(Fe) composite.