Publications by authors named "Abner A Reyes"
Article Synopsis
- Chronic exposure to cocaine leads to lasting changes in the brain's genetic structure, particularly in the nucleus accumbens, which plays a key role in motivation and addiction.
- After withdrawing from cocaine, the depletion of a specific histone variant (H2A.Z) occurs, resulting in increased gene expression linked to relapse behavior among certain neurons (D1 MSNs).
- The study highlights how the chaperone ANP32E regulates H2A.Z removal, suggesting potential therapeutic targets for preventing the negative effects of cocaine on brain function and behavior.
